Facile Synthesis of Red/NIR AIE Luminogens with Simple Structures, Bright Emissions, and High Photostabilities, and Their Applications for Specific Imaging of Lipid Droplets and Image-Guided Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201704039
Abstract: Red/near-infrared (NIR) fluorescent molecules with aggregation-induced emission (AIE) characteristics are of great interest in bioimaging and therapeutic applications. However, their complicated synthetic approaches remain the major barrier to implementing these applications. Herein, a one-pot synthetic… read more here.
Keywords: red nir; bright emissions; aie luminogens; lipid droplets ... See more keywords
Molecular Engineering of Efficient Singlet Oxygen Generators with Near‐Infrared AIE Features for Mitochondrial Targeted Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202104026
Abstract: Aggregation‐caused fluorescence quenching with insufficient production of reactive oxygen species (ROS) has limited the application of photosensitizers (PSs) in fluorescence‐imaging‐guided photodynamic therapy (PDT). Aggregation‐induced emission PSs (AIE‐PSs) exhibit enhanced fluorescence intensity and a high efficiency… read more here.
Keywords: aie; photodynamic therapy; fluorescence; aie pss ... See more keywords
Photo‐Responsive Fluorescent Materials with Aggregation‐Induced Emission Characteristics
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Optical Materials"
DOI: 10.1002/adom.202001362
Abstract: Stimuli‐responsive fluorescent materials with aggregation‐induced emission (AIE) characteristics have attracted increasing attention owing to their advantages of bright fluorescence in the solid state and the ability to tune the structures and physicochemical performances in response… read more here.
Keywords: aie; fluorescent materials; responsive fluorescent; photo responsive ... See more keywords
AIE Multinuclear Ir(III) Complexes for Biocompatible Organic Nanoparticles with Highly Enhanced Photodynamic Performance
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201802050
Abstract: Abstract The singlet oxygen (1O2) generation ability of a photosensitizer (PS) is pivotal for photodynamic therapy (PDT). Transition metal complexes are effective PSs, owing to their high 1O2 generation ability. However, non‐negligible cellular toxicity, poor… read more here.
Keywords: generation ability; iii; iii complexes; aie ... See more keywords
Discovery of Fluorescent Naturally‐Occurring Inhibitor of SARS‐CoV‐2 Main Protease by AIE Fluorescent Probe
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400311
Abstract: Target‐based high‐throughput screening (HTS) is an efficient way to identify potent drugs. However, the accuracy of HTS could be affected by Pan‐Assay Interference Compounds (PAINS). One reason for the generation of PAINS is that the… read more here.
Keywords: fluorescent; main protease; fluorescent probe; aie ... See more keywords
In Situ Probing Intracellular Drug Release from Redox-Responsive Micelles by United FRET and AIE.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201700339
Abstract: Redox-responsive micelles are versatile nanoplatforms for on-demand drug delivery, but the in situ evaluation of drug release is challenging. Fluorescence resonance energy transfer (FRET) technique shows potential for addressing this, while the aggregation-caused quenching effect… read more here.
Keywords: redox responsive; responsive micelles; drug; drug release ... See more keywords
A Fluorescent Hydrogel with AIE Emission for Dehydration-Visualizable Wearable Sensors.
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202400279
Abstract: Hydrogel-based wearable sensors eventually experience dehydration, which negatively impacts their function, leading to decreased sensitivity. Monitoring the real-time water retention rate and sensing performance of wearable flexible sensors without dismantling them remains a significant difficulty.… read more here.
Keywords: water retention; wearable sensors; hydrogel; emission ... See more keywords
Substituent Effect on AIE mechanism of two coumarin derivatives: uncommon TICT fluorescence in aggregation state.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of fluorescence"
DOI: 10.1007/s10895-022-02933-2
Abstract: Two coumarin derivatives, 7-diethylamino-3-(4-nitrophenyl)coumarin (DNC) and 7-hydroxy-3-(4-nitrophenyl)coumarin (HNC), were synthesized via Knoevenagel condensation of salicylaldehyde derivatives with 4-nitrophenylacetonitrile and then cyclization reaction. Both of them were characterized by single-crystal X-ray diffraction. The molecules of DNC… read more here.
Keywords: aie; two coumarin; coumarin; fluorescence ... See more keywords
Seronegative autoimmune enteropathy with duodenal sparing and colonic clues in an adult female
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-020-01336-9
Abstract: Autoimmune enteropathy (AIE) is a rare immune disorder of the gut seldom found in adults and characterized by uncontrollable diarrhea resulting in malabsorption. While AIE is known to be pan-enteric, virtually all cases have presented… read more here.
Keywords: aie; seronegative autoimmune; autoimmune enteropathy; duodenal sparing ... See more keywords
AIE-MOF materials for biological applications.
Sign Up to like & getrecommendations! Published in 2021 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2021.06.013
Abstract: Metal-Organic Frameworks (MOFs), coming under the realm of coordination chemistry, are unparalleled and the most studied among the group of porous materials. Structurally, these are well-defined three-dimensional crystalline products that can be tuned for various… read more here.
Keywords: mof materials; aie mof; materials biological; biological applications ... See more keywords
Aggregation-induced emission (AIE) fluorophores as imaging tools to trace the biological fate of nano-based drug delivery systems.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2018.12.004
Abstract: The vigorous development of nanotechnology has been accompanied by an equally strong interest and research efforts in nano-based drug delivery systems (NDDSs). However, only a few NDDSs have been translated into clinic thus far. One… read more here.
Keywords: aie; drug delivery; nano based; aie fluorophores ... See more keywords