AIF: an acquired metabolic liability in lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cell Research"
DOI: 10.1038/s41422-019-0197-9
Abstract: Apoptosis-inducing factor has two roles: acting as an apoptosis effector and maintaining mitochondrial metabolism. A recent study uncouples these roles and finds that only the mitochondrial functions are required for tumorigenesis in mice. Hallmarks of… read more here.
Keywords: apoptosis; lung; lung cancer; aif ... See more keywords
Apoptosis-Inducing Factor 2 (AIF-2) Mediates a Caspase-Independent Apoptotic Pathway in the Tropical Sea Cucumber (Holothuria leucospilota)
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DOI: 10.3390/ijms23063008
Abstract: Apoptosis, also known as programmed cell death, is a biological process that is critical for embryonic development, organic differentiation, and tissue homeostasis of organisms. As an essential mitochondrial flavoprotein, the apoptosis-inducing factor (AIF) can directly… read more here.
Keywords: apoptosis; apoptotic pathway; hlaif; aif ... See more keywords
MicroRNA-181a-5p Curbs Osteogenic Differentiation and Bone Formation Partially Through Impairing Runx1-Dependent Inhibition of AIF-1 Transcription
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2022.1516
Abstract: Background Evidence has revealed the involvement of microRNAs (miRNAs) in modulating osteogenic differentiation, implying the promise of miRNA-based therapies for treating osteoporosis. This study investigated whether miR-181a-5p influences osteogenic differentiation and bone formation and aimed… read more here.
Keywords: mir 181a; bone formation; aif; osteogenic differentiation ... See more keywords