AIFM2 blocks ferroptosis independent of ubiquinol metabolism.
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DOI: 10.1016/j.bbrc.2020.01.066
Abstract: Ferroptosis is a multi-step regulated cell death that is characterized by excessive iron accumulation and lipid peroxidation. Cancer cells can acquire resistance to ferroptosis by the upregulation of anti-ferroptotic proteins or by the downregulation of… read more here.
Keywords: aifm2; mechanism; blocks ferroptosis; aifm2 blocks ... See more keywords