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Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.0c06348
Abstract: An α-amido cyclobutanone possessing a C10 hydrocarbon tail was designed as a potential transition-state mimetic for the quorum-quenching metallo-γ-lactonase autoinducer inactivator A (AiiA) with the support of in-house modeling techniques and found to be a…
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Keywords:
aiia;
inhibitor;
cyclobutanone;
active site ... See more keywords
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Published in 2019 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2019.00063
Abstract: Background: N-acylated homoserine lactone lactonase which cleave the Acyl homoserine lactone molecules produced by biofilm-forming pathogens and silver nano-particles (AgNPs), are known for their antibacterial effect against several Gram-positive and Gram-negative bacteria. In this study,…
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Keywords:
aiia;
silver nanoparticles;
lactonase leads;
nanoparticles lactonase ... See more keywords