Articles with "aim2 casp11" as a keyword



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Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10020311

Abstract: N-methyl-N-nitrosourea (NMU) is widely used to model oxidative stress and inflammation mediated retinal neurodegeneration. Wedelolactone (WD) is known to have antioxidant, anti-inflammatory, and neuroprotective roles. This study tested the therapeutic potential of WD in NMU-induced… read more here.

Keywords: retinal neurodegeneration; induced retinal; neurodegeneration; wedelolactone ... See more keywords