Unravelling the apoptotic mechanisms in T-lymphocytes in an animal model for pollen induced airway allergy and studying the impact of specific immunotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.11.008
Abstract: Asthma is a chronic inflammatory disorder of the airways, increasing in prevalence worldwide. Reduced T cell apoptosis may interfere with the down-regulation of an immune response resulting in T cell accumulation contributing to the chronic… read more here.
Keywords: immunotherapy; apoptosis; induced airway; pollen induced ... See more keywords
Modulation of regulatory T cells by intranasal allergen immunotherapy in an experimental rat model of airway allergy
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.03.017
Abstract: Abstract Allergic airway diseases such as asthma and allergic rhinitis are increasing in prevalence worldwide. The theory of an altered Th1/Th2 balance in allergic diathesis has recently been termed a “procrustean paradigm” as it failed… read more here.
Keywords: treg cells; immunotherapy; allergen immunotherapy; intranasal allergen ... See more keywords
Airway allergy causes alveolar macrophage death, profound alveolar disorganization and surfactant dysfunction
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1125984
Abstract: Respiratory disorders caused by allergy have been associated to bronchiolar inflammation leading to life-threatening airway narrowing. However, whether airway allergy causes alveolar dysfunction contributing to the pathology of allergic asthma remains unaddressed. To explore whether… read more here.
Keywords: airway allergy; pathology; dysfunction; allergy causes ... See more keywords