Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles
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DOI: 10.1002/ppul.23984
Abstract: Protracted bacterial bronchitis (PBB) is a common cause of prolonged cough in young children, and may be a precursor of bronchiectasis. Bacteria are often present in the lower airways in both PBB and bronchiectasis and… read more here.
Keywords: airway cells; bronchiectasis; cells protracted; bacterial bronchitis ... See more keywords
E-cigarette vapour enhances pneumococcal adherence to airway epithelial cells
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DOI: 10.1183/13993003.01592-2017
Abstract: E-cigarette vapour contains free radicals with the potential to induce oxidative stress. Since oxidative stress in airway cells increases platelet-activating factor receptor (PAFR) expression, and PAFR is co-opted by pneumococci to adhere to host cells,… read more here.
Keywords: airway cells; vapour; adhesion; pafr expression ... See more keywords
Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells
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DOI: 10.26508/lsa.202201813
Abstract: The expression of the virus-activating protease TMPRSS2 in airway cells is enhanced by bacterial components. This may contribute to virus activation and replication in co-infections of IAV and bacteria. read more here.
Keywords: regulated bacterial; tmprss2 regulated; expression; expression tmprss2 ... See more keywords
Airway M Cells Arise in the Lower Airway Due to RANKL Signaling and Reside in the Bronchiolar Epithelium Associated With iBALT in Murine Models of Respiratory Disease
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DOI: 10.3389/fimmu.2019.01323
Abstract: Microfold (M) cells residing in the follicle-associated epithelium of mucosa-associated lymphoid tissues are specialized for sampling luminal antigens to initiate mucosal immune responses. In the past decade, glycoprotein 2 (GP2) and Tnfaip2 were identified as… read more here.
Keywords: airway cells; lower respiratory; epithelium; airway ... See more keywords
Virus Mimetic Poly (I:C)-Primed Airway Exosome-like Particles Enter Brain and Induce Inflammatory Cytokines and Mitochondrial Reactive Oxygen Species in Microglia
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DOI: 10.3390/biology10121359
Abstract: Simple Summary Upper respiratory tract viral infections are among the most common diseases. The blood-brain barrier protects the brain from direct invasion of pathogens. However, the cells share their content with other cells in small… read more here.
Keywords: poly primed; enter brain; airway cells; primed airway ... See more keywords