IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation
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DOI: 10.1038/s41598-018-36440-x
Abstract: Certain proteases derived from house dust mites and plants are considered to trigger initiation of allergic airway inflammation by disrupting tight junctions between epithelial cells. It is known that inhalation of proteases such as house… read more here.
Keywords: protease; inflammation; airway inflammation; airway eosinophilia ... See more keywords
Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin
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DOI: 10.1038/s41598-021-85277-4
Abstract: Exposure to various antigens derived from house dust mites (HDM) is considered to be a risk factor for development of certain allergic diseases such as atopic asthma, atopic dermatitis, rhinitis and conjunctivitis. Chitin is an… read more here.
Keywords: thymic stromal; stromal lymphopoietin; interleukin thymic; airway eosinophilia ... See more keywords
Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD
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DOI: 10.3390/biomedicines10061412
Abstract: The associations between airway eosinophilia, measured in sputum or peripheral blood, and acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are inconsistent. We therefore aimed to determine the association between eosinophilia in bronchoalveolar lavage (BAL)… read more here.
Keywords: bal eosinophilia; airway eosinophilia; bronchoalveolar lavage; eosinophilia bronchoalveolar ... See more keywords
Blood Eosinophils and Exhaled Nitric Oxide: Surrogate Biomarkers of Airway Eosinophilia in Stable COPD and Exacerbation
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DOI: 10.3390/biomedicines10092128
Abstract: In recent years, tremendous efforts have been devoted to characterizing the inflammatory processes in chronic obstructive pulmonary disease (COPD) in order to provide more personalized treatment for COPD patients. While it has proved difficult to… read more here.
Keywords: copd; surrogate biomarkers; airway eosinophilia; exhaled nitric ... See more keywords
Heterogeneous Response of Airway Eosinophilia to Anti-IL-5 Biologics in Severe Asthma Patients
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DOI: 10.3390/jpm12010070
Abstract: Many questions concerning responders (R) and nonresponders (NR) in severe eosinophilic asthma (SEA) after blocking the IL-5 (interleukin 5) pathway are still not clear, especially regarding the early parameters of response to biologics in personalized… read more here.
Keywords: response airway; eosinophilia anti; airway eosinophilia; heterogeneous response ... See more keywords