Th17 associated cytokines in sputum samples from patients with cystic fibrosis.
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens and disease"
DOI: 10.1093/femspd/ftaa050
Abstract: Cystic fibrosis (CF) is a genetic disease leading to chronic bacterial airway infection and inflammation. T helper 17 (Th17) cells are identified by their production of interleukin (IL)-17A, which recruit neutrophils to the site of… read more here.
Keywords: cystic fibrosis; cytokines sputum; th17 associated; associated cytokines ... See more keywords
The Elusive Role of Airway Infection in Cystic Fibrosis Exacerbation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piac062
Abstract: Cystic fibrosis (CF) pulmonary exacerbations (PEx) are clinical events that commonly result in increased treatment burden, decreased quality of life, and accelerated lung disease progression. CF PEx have historically been approached as though dealing with… read more here.
Keywords: airway infection; role airway; fibrosis; cystic fibrosis ... See more keywords
Age‐specific associations of early daycare, older siblings, severe airway infection, and preterm birth with subsequent atopic diseases
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DOI: 10.1111/pai.13771
Abstract: The effects of infection and developmental adaptations in infancy on the prevalence of subsequent atopy‐related diseases at different ages during childhood are not fully determined. This study aims to examine the similarities and differences in… read more here.
Keywords: older siblings; age specific; daycare older; severe airway ... See more keywords
Lower Airway Infection in Preschool Children with Cystic Fibrosis: An International Comparison
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201910-2064le
Abstract: methods of microbiological screening (2). It also aligns with the accumulating evidence that increasing prevalence is associated with increasingly aggressive use of antibiotics in this cohort, and we would support the call for further work… read more here.
Keywords: cystic fibrosis; infection; microbiology; pulmonary exacerbations ... See more keywords
The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073513
Abstract: The advent of Cystic fibrosis transmembrane receptor (CFTR) modulators in 2012 was a critical event in the history of cystic fibrosis (CF) treatment. Unlike traditional therapies that target downstream effects of CFTR dysfunction, CFTR modulators… read more here.
Keywords: cystic fibrosis; airway infection; cftr modulators; cftr ... See more keywords