T cells and ILC2s are major effector cells in influenza‐induced exacerbation of allergic airway inflammation in mice
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201747421
Abstract: Influenza virus infection is an important cause of severe asthma exacerbations, but it remains unclear how a Th1‐mediated antiviral response triggers a prototypical Th2 disease. We investigated CD4+ T cells and group 2 innate lymphoid… read more here.
Keywords: cells ilc2s; induced exacerbation; airway inflammation; influenza induced ... See more keywords
Exopolysaccharide from Lacticaseibacillus rhamnosus induces IgA production in airways and alleviates allergic airway inflammation in mouse model.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250135
Abstract: The currently observed high prevalence of allergic diseases has been associated with changes in microbial exposure in industrialized countries. Defined bacterial components represent a new strategy for modulating the allergic immune response. We show that… read more here.
Keywords: airway inflammation; allergic airway; lacticaseibacillus rhamnosus; mouse model ... See more keywords
Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4017
Abstract: We recently demonstrated that benzo[a]pyrene (BaP), the aryl hydrocarbon receptor (AhR) ligand, directly contributes to aggravation of cutaneous allergy in a mouse model of allergic dermatitis. The present study aimed to determine whether BaP‐induced AhR… read more here.
Keywords: airway inflammation; expression; activation; mouse model ... See more keywords
Fingolimod attenuates ovalbumin‐induced airway inflammation via inhibiting MAPK/ERK signaling in mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23266
Abstract: The current study was designed to investigate the potential anti‐inflammatory and antioxidant effects of fingolimod against Ovalbumin (Ova)‐induced allergic airway inflammation compared to dexamethasone. Fingolimod was given (0.5 mg/kg/day, p.o.) for sensitized mice 1 h before Ova… read more here.
Keywords: inflammation; ova induced; fingolimod; airway inflammation ... See more keywords
Assessment of airway inflammation and remodeling in children with severe asthma: The next challenge
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24051
Abstract: Severe Asthma (SA) in children is relatively rare, affecting 2-5% of the asthmatic pediatric population. However, its burden is disproportionally high, as children with SA experience frequent asthma attacks, have a reduced quality of life,… read more here.
Keywords: inflammation remodeling; inflammation; airway inflammation; bronchial mucosa ... See more keywords
Abscisic acid suppresses the activation of NLRP3 inflammasome and oxidative stress in murine allergic airway inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7051
Abstract: Abscisic acid (ABA), a well‐known natural phytohormone reportedly exerts anti‐inflammatory and anti‐oxidative properties in diabetes and colitis. However, the efficacy of ABA against allergic airway inflammation and the underlying mechanism remain unknown. Herein, an OVA‐induced… read more here.
Keywords: allergic airway; inflammation; airway inflammation; nlrp3 inflammasome ... See more keywords
Acute iron oxide nanoparticles exposure induced murine eosinophilic airway inflammation via TLR2 and TLR4 signaling
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23455
Abstract: Iron oxide nanoparticles (Fe2O3 NPs) is the main component of air pollution particles in urban rail transit environment. People are more exposed to Fe2O3 NPs, however, the studies on relationship between Fe2O3 NPs and respiratory… read more here.
Keywords: fe2o3 nps; airway inflammation; tlr2 tlr4;
OVA-Induced Allergic Airway Inflammation Mouse Model.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8994-2_28
Abstract: Asthma is a worldwide public health issue, affecting the sufferer's quality of life. Many researchers are extensively studying the cellular processes involved in the affected airways. Experimental asthma using animals has been performed for a… read more here.
Keywords: allergic airway; inflammation; airway inflammation; induced allergic ... See more keywords
Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00907-8
Abstract: Allergic asthma is characterized by chronic airway inflammation and is constantly associated with anxiety disorder. Recent studies showed bidirectional interaction between the brain and the lung tissue. However, where and how the brain is affected in… read more here.
Keywords: airway inflammation; like behavior; allergic asthma; anxiety like ... See more keywords
Different effects of acetyl-CoA carboxylase inhibitor TOFA on airway inflammation and airway resistance in a mice model of asthma
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological Reports"
DOI: 10.1007/s43440-019-00027-8
Abstract: Background and objective Acetyl CoA carboxylase (ACC) regulates the differentiation of Th1, Th2, Th17 cells and Treg cells, which play a critical role in airway inflammation of asthma. Here we investigated the role of ACC… read more here.
Keywords: tofa; airway inflammation; expression; acetyl coa ... See more keywords
FABP4 induces asthmatic airway epithelial barrier dysfunction via ROS-activated FoxM1.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.11.106
Abstract: Functional abnormal airway epithelial cells, along with activated inflammatory cells, resulting in chronic airway inflammation, are considered as the characteristic of asthma. Fatty Acid Binding Protein 4 (FABP4) takes part in glucose and lipid homeostasis,… read more here.
Keywords: barrier; barrier dysfunction; airway inflammation; airway epithelial ... See more keywords