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   Articles with "airway microbiome" as a keyword



Upper airway microbiome changes in children with sickle cell disease during vaso‐occlusive and acute chest syndrome episodes

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recommendations! Published in 2020 at "American Journal of Hematology"

DOI: 10.1002/ajh.25931

Abstract: AUTHOR CONTRIBUTIONS Rose-Marie Amini and Panagiotis Baliakas designed the study and wrote the manuscript. Gunilla Enblad, Maysaa Abdulla and Rose-Marie Amini performed data collection. Maysaa Abdulla and Rose-Marie Amini reevaluated the diagnoses. PB, Rose-Marie Amini,… read more here.

Keywords: marie amini; microbiome changes; rose marie; upper airway ... See more keywords

Airway Microbiome Dynamics and Relationship to Ventilator-Associated Infection in Intubated Pediatric Patients.

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recommendations! Published in 2021 at "Pediatric pulmonology"

DOI: 10.1002/ppul.25769

Abstract: BACKGROUND Little is known about the airway microbiome in intubated mechanically ventilated children. We sought to characterize the airway microbiome longitudinally and in association with clinical variables and possible ventilator-associated infection (VAI). METHODS Serial tracheal… read more here.

Keywords: airway microbiome; vain; associated infection; ventilator associated ... See more keywords

Metagenomic whole genome shotgun analysis of the airway microbiome in laryngotracheal stenosis: a pilot study

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-11468-y

Abstract: The airway microbiome has been implicated in the pathogenesis of laryngotracheal stenosis (LTS), yet prior studies using 16 S rRNA sequencing have limited sub-genus level resolution. Metagenomic whole genome shotgun sequencing (mWGS) allows for strain-level… read more here.

Keywords: metagenomic whole; whole genome; genome shotgun; pilot study ... See more keywords

Supplemental Oxygen Alters the Airway Microbiome in Cystic Fibrosis

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recommendations! Published in 2022 at "mSystems"

DOI: 10.1128/msystems.00364-22

Abstract: The airway microbiome in persons with cystic fibrosis (pwCF) is correlated with lung function and disease severity. Supplemental oxygen use is common in more advanced CF, yet its role in perturbing airway microbial communities is… read more here.

Keywords: supplemental oxygen; oxygen; pwcf; airway microbiome ... See more keywords
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Integrative study of the upper and lower airway microbiome and transcriptome in asthma.

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recommendations! Published in 2020 at "JCI insight"

DOI: 10.1172/jci.insight.133707

Abstract: Relatively little is known about interactions between the airway microbiome and airway host transcriptome in asthma. Since asthma affects and is affected by the entire airway, studying the upper (e.g., nasal) and lower (e.g., bronchial)… read more here.

Keywords: asthmatic children; integrative study; airway microbiome; asthma ... See more keywords

The MUSIC trial: harmonising our understanding of inhaled corticosteroids and the COPD airway microbiome

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recommendations! Published in 2025 at "European Respiratory Journal"

DOI: 10.1183/13993003.01605-2025

Abstract: Extract COPD is projected to affect more than 600 million people by 2050 [1] and contributes to approximately 5% of global deaths annually [2]. Acute exacerbations of COPD (AECOPD) are associated with accelerated loss of lung… read more here.

Keywords: copd airway; inhaled corticosteroids; corticosteroids copd; music trial ... See more keywords

Prospective case-control study describing the lower airway microbiome in pre-school children with cystic fibrosis

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recommendations! Published in 2018 at "European Respiratory Journal"

DOI: 10.1183/13993003.congress-2018.oa509

Abstract: Introduction: The traditional paradigm that the lung is a sterile environment no longer holds true in the current era of the microbiome. Aim: Our aim was to describe the lower airway microbiome in pre-school children… read more here.

Keywords: microbiome pre; school children; pre school; diversity ... See more keywords
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Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4

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recommendations! Published in 2021 at "BMC Genomics"

DOI: 10.1186/s12864-020-07252-z

Abstract: Background Studies on the airway microbiome have been performed using a wide range of laboratory protocols for high-throughput sequencing of the bacterial 16S ribosomal RNA (16S rRNA) gene. We sought to determine the impact of… read more here.

Keywords: airway microbiome; pcr steps; number; 16s rrna ... See more keywords

Inhaled nanomaterials and the respiratory microbiome: clinical, immunological and toxicological perspectives

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recommendations! Published in 2018 at "Particle and Fibre Toxicology"

DOI: 10.1186/s12989-018-0282-0

Abstract: Our development and usage of engineered nanomaterials has grown exponentially despite concerns about their unfavourable cardiorespiratory consequence, one that parallels ambient ultrafine particle exposure from vehicle emissions. Most research in the field has so far… read more here.

Keywords: nanoparticle; clinical immunological; airway microbiome; human airway ... See more keywords

Dysglycemia and the airway microbiome in cystic fibrosis

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recommendations! Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0331847

Abstract: Background Cystic fibrosis-related diabetes (CFRD) is one of the most common non-pulmonary complications in people living with cystic fibrosis (pwCF), seen in up to 50% of adults. Even when correcting for severity of CFTR mutations,… read more here.

Keywords: fibrosis; dysglycemia; lung function; cystic fibrosis ... See more keywords

Distinct Airway Microbiome and Metabolite Profiles in Eosinophilic and Neutrophilic Asthma

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recommendations! Published in 2025 at "Journal of Asthma and Allergy"

DOI: 10.2147/jaa.s521800

Abstract: Background Asthma is a chronic, heterogeneous disease driven by inflammatory phenotypes, primarily eosinophilic asthma (EA) and neutrophilic asthma (NEA). While allergen triggers are well-known, the role of the airway microbiome and metabolites in asthma exacerbations… read more here.

Keywords: airway microbiome; distinct airway; external cohort; neutrophilic asthma ... See more keywords