Articles with "airway microbiome" as a keyword



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Upper airway microbiome changes in children with sickle cell disease during vaso‐occlusive and acute chest syndrome episodes

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Published in 2020 at "American Journal of Hematology"

DOI: 10.1002/ajh.25931

Abstract: AUTHOR CONTRIBUTIONS Rose-Marie Amini and Panagiotis Baliakas designed the study and wrote the manuscript. Gunilla Enblad, Maysaa Abdulla and Rose-Marie Amini performed data collection. Maysaa Abdulla and Rose-Marie Amini reevaluated the diagnoses. PB, Rose-Marie Amini,… read more here.

Keywords: marie amini; microbiome changes; rose marie; upper airway ... See more keywords
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Airway Microbiome Dynamics and Relationship to Ventilator-Associated Infection in Intubated Pediatric Patients.

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Published in 2021 at "Pediatric pulmonology"

DOI: 10.1002/ppul.25769

Abstract: BACKGROUND Little is known about the airway microbiome in intubated mechanically ventilated children. We sought to characterize the airway microbiome longitudinally and in association with clinical variables and possible ventilator-associated infection (VAI). METHODS Serial tracheal… read more here.

Keywords: airway microbiome; vain; associated infection; ventilator associated ... See more keywords
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Supplemental Oxygen Alters the Airway Microbiome in Cystic Fibrosis

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Published in 2022 at "mSystems"

DOI: 10.1128/msystems.00364-22

Abstract: The airway microbiome in persons with cystic fibrosis (pwCF) is correlated with lung function and disease severity. Supplemental oxygen use is common in more advanced CF, yet its role in perturbing airway microbial communities is… read more here.

Keywords: supplemental oxygen; oxygen; pwcf; airway microbiome ... See more keywords
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Integrative study of the upper and lower airway microbiome and transcriptome in asthma.

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Published in 2020 at "JCI insight"

DOI: 10.1172/jci.insight.133707

Abstract: Relatively little is known about interactions between the airway microbiome and airway host transcriptome in asthma. Since asthma affects and is affected by the entire airway, studying the upper (e.g., nasal) and lower (e.g., bronchial)… read more here.

Keywords: asthmatic children; integrative study; airway microbiome; asthma ... See more keywords
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Prospective case-control study describing the lower airway microbiome in pre-school children with cystic fibrosis

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Published in 2018 at "European Respiratory Journal"

DOI: 10.1183/13993003.congress-2018.oa509

Abstract: Introduction: The traditional paradigm that the lung is a sterile environment no longer holds true in the current era of the microbiome. Aim: Our aim was to describe the lower airway microbiome in pre-school children… read more here.

Keywords: microbiome pre; school children; pre school; diversity ... See more keywords
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Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4

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Published in 2021 at "BMC Genomics"

DOI: 10.1186/s12864-020-07252-z

Abstract: Background Studies on the airway microbiome have been performed using a wide range of laboratory protocols for high-throughput sequencing of the bacterial 16S ribosomal RNA (16S rRNA) gene. We sought to determine the impact of… read more here.

Keywords: airway microbiome; pcr steps; number; 16s rrna ... See more keywords
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Inhaled nanomaterials and the respiratory microbiome: clinical, immunological and toxicological perspectives

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Published in 2018 at "Particle and Fibre Toxicology"

DOI: 10.1186/s12989-018-0282-0

Abstract: Our development and usage of engineered nanomaterials has grown exponentially despite concerns about their unfavourable cardiorespiratory consequence, one that parallels ambient ultrafine particle exposure from vehicle emissions. Most research in the field has so far… read more here.

Keywords: nanoparticle; clinical immunological; airway microbiome; human airway ... See more keywords
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Using metabolic potential within the airway microbiome as predictors of clinical state in persons with cystic fibrosis

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Published in 2023 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.1082125

Abstract: Introduction Pulmonary exacerbations (PEx) in persons with cystic fibrosis (CF) are primarily related to acute or chronic inflammation associated with bacterial lung infections, which may be caused by several bacteria that activate similar bacterial genes… read more here.

Keywords: persons cystic; bacterial species; clinical state; airway microbiome ... See more keywords
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Human matters in asthma: Considering the microbiome in pulmonary health

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1020133

Abstract: Microbial communities form an important symbiotic ecosystem within humans and have direct effects on health and well-being. Numerous exogenous factors including airborne triggers, diet, and drugs impact these established, but fragile communities across the human… read more here.

Keywords: health; matters asthma; asthma; human matters ... See more keywords
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COPD AND THE AIRWAY MICROBIOME: WHAT RESPIROLOGISTS NEED TO KNOW.

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Published in 2023 at "Tuberculosis and respiratory diseases"

DOI: 10.4046/trd.2023.0015

Abstract: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. The lower airways contain a rich and diverse microbiome, which may play a significant regulatory role in both health and disease.… read more here.

Keywords: microbiome respirologists; copd airway; need know; airway microbiome ... See more keywords
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Airway Microbiome in Different Inflammatory Phenotypes of Asthma: A Cross-Sectional Study in Northeast China

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Published in 2019 at "International Journal of Medical Sciences"

DOI: 10.7150/ijms.29433

Abstract: Background and Objective: Asthma is a common respiratory disease with a high prevalence and morbidity that can seriously affect quality of life. Microbial colonization of the airway may participate in the pathogenesis of asthma, however… read more here.

Keywords: cross sectional; sectional study; study; airway microbiome ... See more keywords