The airway microbiota in early cystic fibrosis lung disease
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23782
Abstract: Infection plays a critical role in the pathogenesis of cystic fibrosis (CF) lung disease. Over the past two decades, the application of molecular and extended culture‐based techniques to microbial analysis has changed our understanding of… read more here.
Keywords: cystic fibrosis; lung disease; disease; fibrosis lung ... See more keywords
Fungal and Bacterial Diversity of Airway Microbiota in Adults with Cystic Fibrosis: Concordance Between Conventional Methods and Ultra-Deep Sequencing, and Their Practical use in the Clinical Laboratory
Sign Up to like & getrecommendations! Published in 2017 at "Mycopathologia"
DOI: 10.1007/s11046-017-0185-x
Abstract: Given the complexity of the airway microbiota in the respiratory tract of cystic fibrosis (CF) patients, it seems crucial to compile the most exhaustive and exact list of the microbial communities inhabiting CF airways. The… read more here.
Keywords: ultra deep; cystic fibrosis; diversity; fungal bacterial ... See more keywords
Airway microbiota in children with bronchial mucus plugs caused by Mycoplasma pneumoniae pneumonia.
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2020.105902
Abstract: BACKGROUND There is increasing evidence for a role of lung microbiota in the pathogenesis of Mycoplasma pneumoniae pneumonia (MPP). However, the alterations of lung microbiota in MPP with bronchial mucus plugs and its role in… read more here.
Keywords: bronchial mucus; mucus plugs; mpp children; mucus ... See more keywords
The airway microbiota of non‐small cell lung cancer patients and its relationship to tumor stage and EGFR gene mutation
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DOI: 10.1111/1759-7714.14340
Abstract: Accumulating studies have suggested the airway microbiota in lung cancer patients is significantly different from that of healthy controls. However, little is known about the relationship between airway microbiota and important clinical parameters of lung… read more here.
Keywords: lung cancer; airway microbiota; egfr gene; cancer patients ... See more keywords
The Airway Microbiota Signatures of Infection and Rejection in Lung Transplant Recipients
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DOI: 10.1128/spectrum.00344-21
Abstract: Survival after LT is limited compared with other solid organ transplantations mainly due to infection- and rejection-related complications. Differentiating infection from rejection is one of the most important challenges to face after LT. ABSTRACT Infection… read more here.
Keywords: airway microbiota; infection acute; infection; rejection ... See more keywords
Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02251-22
Abstract: The management of cystic fibrosis has been transformed recently by the advent of CFTR modulators, including lumacaftor-ivacaftor. However, the effects of such therapies on the airway ecosystem, particularly on the microbiota-mycobiota and local inflammation, which… read more here.
Keywords: airway microbiota; inflammation; lumacaftor ivacaftor; microbiota mycobiota ... See more keywords
The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis
Sign Up to like & getrecommendations! Published in 2017 at "Thorax"
DOI: 10.1136/thoraxjnl-2016-209279
Abstract: Rationale In infants and young children with cystic fibrosis, lower airway infection and inflammation are associated with adverse respiratory outcomes. However, the role of lower airway microbiota in the pathogenesis of early cystic fibrosis lung… read more here.
Keywords: airway microbiota; cystic fibrosis; lower airway; age ... See more keywords
The airway microbiota and exacerbations of COPD
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DOI: 10.1183/23120541.00168-2020
Abstract: Aim The aim of this study was to investigate whether the compositionality of the lower airway microbiota predicts later exacerbation risk in persons with COPD in a cohort study. Materials and methods We collected lower… read more here.
Keywords: exacerbations copd; microbiota exacerbations; study; copd ... See more keywords
Azithromycin alters spatial and temporal dynamics of airway microbiota in idiopathic pulmonary fibrosis
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DOI: 10.1183/23120541.00720-2022
Abstract: Background: High bacterial burden in lung microbiota predicts progression of idiopathic pulmonary fibrosis (IPF). Azithromycin is a macrolide antibiotic known to alter the lung microbiota in several chronic pulmonary diseases and observational studies have shown… read more here.
Keywords: pulmonary fibrosis; airway microbiota; azithromycin; idiopathic pulmonary ... See more keywords
Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota
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DOI: 10.1186/s40168-020-00895-w
Abstract: Background From early life, children are exposed to a multitude of environmental exposures, which may be of crucial importance for healthy development. Here, the environmental microbiota may be of particular interest as it represents the… read more here.
Keywords: microbiota; airway microbiota; bed dust; fungal community ... See more keywords
The Role of Gut and Airway Microbiota in Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.929752
Abstract: Pulmonary arterial hypertension (PAH) is a severe clinical condition that is characterized pathologically by perivascular inflammation and pulmonary vascular remodeling that ultimately leads to right heart failure. However, current treatments focus on controlling vasoconstriction and… read more here.
Keywords: airway microbiota; arterial hypertension; role; gut airway ... See more keywords