LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "airway remodeling" as a keyword



Shikonin alleviates allergic airway remodeling by inhibiting the ERK‐NF‐&kgr;B signaling pathway

Sign Up to like & get
recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.05.011

Abstract: Abstract Shikonin is a naphthoquinone extracted from the root of Lithospermum erythrorhizon, and has been reported to suppress allergic airway inflammation in mice. However, the underlying mechanisms are unclear and need to be further elucidated.… read more here.

Keywords: allergic airway; alleviates allergic; shikonin alleviates; shikonin ... See more keywords

MiRNA-451a inhibits airway remodeling by targeting Cadherin 11 in an allergic asthma model of neonatal mice.

Sign Up to like & get
recommendations! Published in 2020 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2020.106440

Abstract: Airway remodeling happens in childhood asthma, in parallel with, but not necessarily subsequent to, airway inflammation. The differentiation of airway epithelial cells into myofibroblasts via epithelial-mesenchymal-transition (EMT) is one of the mechanisms underlying airway remodeling.… read more here.

Keywords: cdh11; mirna 451a; asthma model; airway remodeling ... See more keywords
Photo from wikipedia

p62-dependent autophagy in airway smooth muscle cells regulates metabolic reprogramming and promotes airway remodeling.

Sign Up to like & get
recommendations! Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118884

Abstract: AIMS Growing evidence indicates insufficient autophagy is crucial to airway remodeling in asthma. However, it is uncertain whether p62, an autophagy major regulator, mediates the airway remodeling process. This study aimed to evaluate the role… read more here.

Keywords: muscle cells; p62 dependent; smooth muscle; airway remodeling ... See more keywords
Photo from archive.org

Airway Remodeling in Feline Lungs.

Sign Up to like & get
recommendations! Published in 2021 at "Topics in companion animal medicine"

DOI: 10.1016/j.tcam.2021.100587

Abstract: Airway remodeling encompass structural changes that occur as the result of chronic injury and lead to persistently altered airway structure and function. Although this process is known in several human respiratory conditions such as asthma… read more here.

Keywords: medicine; feline lungs; asmcs; remodeling feline ... See more keywords

STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma

Sign Up to like & get
recommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2114557118

Abstract: Significance Stromal-interacting molecule 1 (STIM1) proteins are essential for the function of store-operated Ca2+ entry (SOCE). Using transcriptomics, metabolomics, imaging, and inducible smooth muscle–specific STIM1 knockout mice expressing genetically encoded Ca2+ sensors, we reveal a… read more here.

Keywords: airway smooth; asm; airway remodeling; stim1 ... See more keywords

Correlation between changes in serum YKL-40, LXRs, PPM1A, and TGF-β1 levels and airway remodeling and lung function in patients with bronchial asthma

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Asthma"

DOI: 10.1080/02770903.2023.2301426

Abstract: Abstract Objective This study investigates the correlation between serum levels of YKL-40, LXRs, PPM1A, and TGF-β1 and airway remodeling and lung function in bronchial asthma patients. Methods The study involved 80 bronchial asthma patients and… read more here.

Keywords: airway remodeling; tgf; lung function; ppm1a ... See more keywords
Photo by lunarts from unsplash

Airway remodeling in asthma: update on mechanisms and therapeutic approaches

Sign Up to like & get
recommendations! Published in 2018 at "Current Opinion in Pulmonary Medicine"

DOI: 10.1097/mcp.0000000000000441

Abstract: Purpose of review The term ‘airway remodeling’ reflects changes in the type, quantity, and nature of airway wall components and their organization. The purpose of this review is to look at recent publications on airway… read more here.

Keywords: asthma update; mechanisms therapeutic; therapeutic approaches; remodeling asthma ... See more keywords
Photo by yunu_dinata from unsplash

The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs

Sign Up to like & get
recommendations! Published in 2021 at "Immunology and Cell Biology"

DOI: 10.1111/imcb.12448

Abstract: Allergic airway inflammation is heterogeneous with variability in immune phenotypes observed across asthmatic patients. Inflammation has been thought to directly contribute to airway remodeling in asthma, but clinical data suggest that neutralizing type 2 cytokines… read more here.

Keywords: c57bl mice; airway remodeling; inflammation; mice ... See more keywords

Emerging Concepts in Cytokine Regulation of Airway Remodeling in Asthma

Sign Up to like & get
recommendations! Published in 2025 at "Immunological Reviews"

DOI: 10.1111/imr.70020

Abstract: Asthma, a chronic respiratory condition that has seen a dramatic rise in prevalence over the past few decades, now affects more than 300 million people globally and imposes a significant burden on healthcare systems. The… read more here.

Keywords: emerging concepts; airway remodeling; cytokine regulation; remodeling asthma ... See more keywords

The Correlation between FSTL1 Expression and Airway Remodeling in Asthmatics

Sign Up to like & get
recommendations! Published in 2017 at "Mediators of Inflammation"

DOI: 10.1155/2017/7918472

Abstract: Background Asthma is characterized by airway remodeling. Follistatin-like protein 1 (FSTL1) is an extracellular glycoprotein. Recent studies suggest that FSTL1 may participate in the pathogenesis of asthma. Objectives To analyze the association between FSTL1 and… read more here.

Keywords: correlation fstl1; remodeling asthmatics; fstl1; fstl1 levels ... See more keywords

An Inhibitor of Nuclear Factor-Kappa B Pathway Attenuates the Release of TGF-β1 and Inhibits the Fibrogenic Progress in a Model of Airway Remodeling Induced by Acrolein

Sign Up to like & get
recommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/4984634

Abstract: Airway inflammation, airway hypersecretion, and airway remodeling are believed to be involved in the process of lung fibrosis. Nowadays, acrolein is widely used to establish the model of airway remodeling. An active component of propolis,… read more here.

Keywords: model airway; induced acrolein; inhibitor; group ... See more keywords