Cigarette whole smoke solutions disturb mucin homeostasis in a human in vitro airway tissue model.
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DOI: 10.1016/j.tox.2018.07.015
Abstract: Many cigarette smoke-associated airway diseases involve alterations in mucin homeostasis. With the rationale that relevant tissue responses can be measured to evaluate the adverse health effects of tobacco products, we assessed changes in mucin secretion… read more here.
Keywords: whole smoke; airway tissue; tissue model; smoke ... See more keywords
Evaluating the Toxicity of Cigarette Whole Smoke Solutions in an Air-Liquid-Interface Human In Vitro Airway Tissue Model
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DOI: 10.1093/toxsci/kfw239
Abstract: Exposure to cigarette smoke causes a multitude of pathological changes leading to tissue damage and disease. Quantifying such changes in highly differentiated in vitro human tissue models may assist in evaluating the toxicity of tobacco… read more here.
Keywords: airway tissue; air liquid; smoke; evaluating toxicity ... See more keywords