Association of Obesity with Quantitative Chest CT Measured Airway Wall Thickness in WTC Workers with Lower Airway Disease
Sign Up to like & getrecommendations! Published in 2019 at "Lung"
DOI: 10.1007/s00408-019-00246-z
Abstract: BackgroundWe previously reported that wall area percent (WAP), a quantitative CT (QCT) indicator of airway wall thickness and, presumably, inflammation, is associated with adverse longitudinal expiratory flow trajectories in WTC workers, but that obesity and… read more here.
Keywords: wap; wtc workers; airway wall; wtc ... See more keywords
Elevated expression of placental growth factor is associated with airway-wall vascular remodelling and thickening in smokers with asthma
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DOI: 10.1038/srep43017
Abstract: The increased expression of placental growth factor (PlGF) in chronic obstructive pulmonary disease and allergy-related asthma suggests its role in the pathogenesis of these diseases. In asthmatic smokers, airway remodelling is accompanied by an accelerated… read more here.
Keywords: vascular remodelling; plgf; placental growth; airway wall ... See more keywords
Airway wall thickness and airflow limitations in asthma assessed in quantitative computed tomography
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/1753466619898598
Abstract: Background: Asthma is a frequent chronic disease of the airways. In spite of the fact that symptoms of asthma are well known, the pathogenesis has not yet been fully understood. Quantitative computed tomography (qCT) of… read more here.
Keywords: computed tomography; airway wall; quantitative computed; wall thickness ... See more keywords
Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma
Sign Up to like & getrecommendations! Published in 2022 at "European Respiratory Journal"
DOI: 10.1183/13993003.01865-2021
Abstract: Background Eosinophils are implicated as effector cells in asthma, but the functional implications of the precise location of eosinophils in the airway wall is poorly understood. We aimed to quantify eosinophils in the different compartments… read more here.
Keywords: inflammation; airway hyperresponsiveness; airway wall; asthma ... See more keywords
Bronchial Thermoplasty and its Impact on Mast Cells in the Asthmatic Airway Wall and Smooth Muscle
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DOI: 10.1183/13993003.congress-2018.pa982
Abstract: Background: Bronchial Thermoplasty (BT) is a bronchoscopic treatment for severe asthma which reduces airway smooth muscle (ASM). The optimal patient responder profile is still under debate. In asthma, mast cell density is increased within the… read more here.
Keywords: mast cells; mast; airway wall; smooth muscle ... See more keywords
Airway wall splice quantitative trait locus analysis reveals novel downstream mechanisms for known asthma single-nucleotide polymorphisms
Sign Up to like & getrecommendations! Published in 2023 at "ERJ Open Research"
DOI: 10.1183/23120541.00413-2022
Abstract: Genome-wide association studies (GWAS) [1] have identified single-nucleotide polymorphisms (SNPs) associated with the presence of asthma. It is notoriously difficult to link identified SNPs to downstream functional effects leading to increased asthma risk. A possible… read more here.
Keywords: trait locus; nucleotide polymorphisms; airway wall; quantitative trait ... See more keywords
The lower respiratory airway wall in children in health and disease
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DOI: 10.1183/23120541.00874-2020
Abstract: Alone or in association with other lung or thorax component disorders, the airway wall (AWW) remains one of the most frequently involved elements in paediatric lung diseases. A myriad of AWW disorders will present with… read more here.
Keywords: lower respiratory; airway wall; aww; disease ... See more keywords
Genome-Wide Association Study of Airway Wall Thickening in a Korean Chronic Obstructive Pulmonary Disease Cohort
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DOI: 10.3390/genes13071258
Abstract: Airway wall thickening (AWT) plays an important pathophysiological role in airway diseases such as chronic obstructive pulmonary disease (COPD). There are only a few studies on the genetic components contributing to AWT in the Korean… read more here.
Keywords: obstructive pulmonary; airway wall; chronic obstructive; wall thickening ... See more keywords
Aspergillus fumigatus—Host Interactions Mediating Airway Wall Remodelling in Asthma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8020159
Abstract: Asthma is a chronic heterogeneous respiratory condition that is mainly associated with sensitivity to airborne agents such as pollen, dust mite products and fungi. Key pathological features include increased airway inflammation and airway wall remodelling.… read more here.
Keywords: aspergillus fumigatus; fumigatus; airway wall; pathology ... See more keywords
Quantitative Assessment of Airway Pathology in Subjects With COPD Using Low-Dose High-Resolution Computed Tomography
Sign Up to like & getrecommendations! Published in 2017 at "Respiratory Care"
DOI: 10.4187/respcare.05186
Abstract: BACKGROUND: The purpose of this study was to correlate airway parameters of COPD determined by low-dose high-resolution computed tomography (HRCT) with pulmonary function testing (PFT) results. METHODS: PFT data were collected for subjects with COPD… read more here.
Keywords: wall area; correlated airway; airway wall; subjects copd ... See more keywords