Angioimmunoblastic T-Cell Lymphoma: Molecular Characterization of Clonal T and B-Cells and a Patient Derived Xenograft Model of Coexisting T and B-Cell Proliferations
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-129131
Abstract: Introduction: Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive type of lymphoma that accounts for about 20% of peripheral T-cell lymphomas with a 5 year overall survival rate of 30%. As most patients relapse… read more here.
Keywords: aitl; tumor cells; rit; model ... See more keywords
Clonal germinal center B cells function as a niche for T-cell lymphoma.
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DOI: 10.1182/blood.2022015451
Abstract: Angioimmunoblastic T-cell lymphoma (AITL) is proposed to be initiated by age-related clonal hematopoiesis (ACH) with TET2 mutations, whereas the G17V RHOA mutation in immature cells with TET2 mutations promotes development of T follicular helper-like tumor… read more here.
Keywords: cell; function niche; cell lymphoma; aitl ... See more keywords
CD56-positive Angioimmunoblastic T-cell Lymphoma Complicated by Chylothorax.
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DOI: 10.2169/internalmedicine.7783-21
Abstract: A 77-year-old woman presented with systemic lymphadenopathy and bilateral pleural effusion. Angioimmunoblastic T-cell lymphoma (AITL) was diagnosed based on the results of a lymph node biopsy. AITL cells expressed the aberrant antigen of CD56. The… read more here.
Keywords: aitl; lymphoma; cd56 positive; complicated chylothorax ... See more keywords