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Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.534775

Abstract: Cell death and sterile inflammation are major mechanisms of renal fibrosis, which eventually develop into end-stage renal disease. “Necroptosis” is a type of caspase-independent regulated cell death, and sterile inflammatory response caused by tissue injury… read more here.

Keywords: fibrosis; ripk3 mlkl; inhibiting necroptosis; fibrosis inhibiting ... See more keywords