Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.10.006
Abstract: Background Acute kidney injury (AKI) may lead to the development of chronic kidney disease (CKD), i.e. AKI-CKD transition, but the underlying mechanism remains largely unclear. Endoplasmic reticulum (ER) stress is characterized by the accumulation of… read more here.
Keywords: chronic kidney; post ischemic; ckd transition; stress ... See more keywords
AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms.
Sign Up to like & getrecommendations! Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2017.06.030
Abstract: Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected. Although AKI-to-CKD transition has been intensively studied, the information of AKI on CKD is very limited. Nonetheless, AKI, when occurring in patients with CKD,… read more here.
Keywords: ckd heightened; heightened injury; aki ckd; ckd ... See more keywords
Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35943-x
Abstract: Acute kidney injury (AKI) and chronic kidney disease (CKD) are considered early and late phases of a pathologic continuum of interconnected disease states. Although changes in gene expression patterns have recently been elucidated for the… read more here.
Keywords: aki ckd; kidney injury; ckd; transcriptional epigenetic ... See more keywords
Urinary angiotensinogen predicts progressive chronic kidney disease after an episode of experimental acute kidney injury.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20180758
Abstract: One of the major obstacles to prevent AKI-CKD transition is the lack of effective methods to follow and predict the ongoing kidney injury after an AKI episode. In the present study, we test the utility… read more here.
Keywords: fibrosis; aki ckd; episode; day ... See more keywords
Oxidative Stress in Animal Models of Acute and Chronic Renal Failure
Sign Up to like & getrecommendations! Published in 2019 at "Disease Markers"
DOI: 10.1155/2019/8690805
Abstract: Introduction Kidney disease is a worldwide health and economic burden, with rising prevalence. The search for biomarkers for earlier and more effective disease screening and monitoring is needed. Oxidative stress has been linked to both,… read more here.
Keywords: oxidative stress; aki ckd; ckd; acute chronic ... See more keywords
AKD—The Time Between AKI and CKD: What Is the Role of the Pharmacist?
Sign Up to like & getrecommendations! Published in 2017 at "Hospital Pharmacy"
DOI: 10.1177/0018578717733561
Abstract: The role of pharmacists in caring for patients with AKD (1) begins with inpatient care at the time of AKI diagnosis, (2) involves patient-pharmacist interaction at hospital discharge, and (3) provides active follow-up care after… read more here.
Keywords: time aki; pharmacist; aki ckd; role ... See more keywords
Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19979
Abstract: Acute kidney injury (AKI) predisposes patients to an increased risk into progressive chronic kidney disease (CKD), however effective treatments are still elusive. This study aimed to investigate the therapeutic efficacy of human adipose-derived MSCs (hAD-MSCs)… read more here.
Keywords: transition; ckd transition; aki ckd; sox9 ... See more keywords
Serum and Urinary NGAL and Cystatin C Levels as Diagnostic Tools for Acute Kidney Injury and Chronic Kidney Disease: A Histobiochemical Comparative Study
Sign Up to like & getrecommendations! Published in 2019 at "Current Pharmaceutical Design"
DOI: 10.2174/1381612825666190516080920
Abstract: High global incidence of acute kidney injury (AKI) is an observable complication in critically ill patients. Long-term disease and medication complexity contribute to devastating chronic kidney disease (CKD), diminishing quality of life. To establish new… read more here.
Keywords: group; disease; aki ckd; ckd ... See more keywords
Identification of common molecular signatures of SARS-CoV-2 infection and its influence on acute kidney injury and chronic kidney disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.961642
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main cause of COVID-19, causing hundreds of millions of confirmed cases and more than 18.2 million deaths worldwide. Acute kidney injury (AKI) is a common complication… read more here.
Keywords: kidney; covid; aki ckd; cov infection ... See more keywords
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1030800
Abstract: Acute kidney injury (AKI) is a common clinical syndrome with complex pathogenesis, characterized by a rapid decline in kidney function in the short term. Worse still, the incomplete recovery from AKI increases the risk of… read more here.
Keywords: cpt2; mediated lipophagy; aki ckd; ckd transition ... See more keywords
Oroxylin A ameliorates AKI-to-CKD transition through maintaining PPARα-BNIP3 signaling-mediated mitochondrial homeostasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.935937
Abstract: Background: Acute kidney injury (AKI) occurs in approximately 7–18% of all hospitalizations, but there are currently no effective drug therapy for preventing AKI or delaying its progression to chronic kidney disease (CKD). Recent studies have… read more here.
Keywords: bnip3; mitochondrial homeostasis; aki ckd; injury ... See more keywords