Nutrient-specific Proteomic Analysis of the Mucin Degrading Bacterium Akkermansia muciniphila.
Sign Up to like & getrecommendations! Published in 2021 at "Proteomics"
DOI: 10.1002/pmic.202100125
Abstract: Akkermansia muciniphila is a prominent mucin-degrading bacterium that acts as a keystone species in regulating the human gut microbiota. Despite recently increasing research into this bacterium and its relevance to human health, a high-resolution database… read more here.
Keywords: bacterium; degrading bacterium; mucin; akkermansia muciniphila ... See more keywords
Alterations of Akkermansia muciniphila in the inflammatory bowel disease patients with washed microbiota transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-020-10948-7
Abstract: Akkermansia muciniphila is a promising probiotic in the gut. This study aimed to determine the presence and abundance of Akkermansia in patients with inflammatory bowel disease (IBD) who underwent washed microbiota transplantation (WMT) in order… read more here.
Keywords: akkermansia muciniphila; disease; abundance; ibd ... See more keywords
A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion.
Sign Up to like & getrecommendations! Published in 2021 at "Cell metabolism"
DOI: 10.1016/j.cmet.2021.05.004
Abstract: Akkermansia muciniphila is a gut commensal known to improve host metabolism. The outer membrane protein Amuc_1100 has been shown to partially replicate these beneficial effects. Here, Yoon et al. (2021) have identified a novel protein (P9)… read more here.
Keywords: akkermansia muciniphila; glp secretion; stimulates glp; muciniphila stimulates ... See more keywords
The Catalytic Acid–Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable α-Retaining and β-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04474
Abstract: Enzymes active on glycosidic bonds are defined according to the stereochemistry of both substrates and products of the reactions they catalyze. The CAZy classification further assigns these enzymes into sequence-based families sharing a common stereochemistry… read more here.
Keywords: conserved gghgg; akkermansia muciniphila; retaining inverting; acid base ... See more keywords
Comparative effects of alive and pasteurized Akkermansia muciniphila on normal diet-fed mice
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DOI: 10.1038/s41598-021-95738-5
Abstract: Recently, Akkermansia muciniphila an anaerobic member of the gut microbiota, has been proposed as a next-generation probiotic. The aim of this study was evaluation of the effect of alive and pasteurized A. muciniphila on health… read more here.
Keywords: normal diet; akkermansia muciniphila; alive pasteurized; pasteurized muciniphila ... See more keywords
The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential
Sign Up to like & getrecommendations! Published in 2022 at "Critical Reviews in Microbiology"
DOI: 10.1080/1040841x.2022.2044286
Abstract: Abstract The role of Akkermansia muciniphila, one of the most abundant microorganisms of the intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity and diabetes. It is considered a next-generation probiotic microorganism.… read more here.
Keywords: akkermansia muciniphila; role; brain functions; muciniphila brain ... See more keywords
Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development
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DOI: 10.1080/19490976.2021.1892441
Abstract: ABSTRACT Mucin-degrading bacteria are densely populated in the intestinal epithelium; however, their interaction with intestinal stem cells (ISCs) and their progeny have not been elucidated. To determine whether mucin-degrading bacteria play a role in gut… read more here.
Keywords: mucin; akkermansia muciniphila; epithelial development; intestinal stem ... See more keywords
Revisiting the role of Akkermansia muciniphila as a therapeutic bacterium
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2078619
Abstract: ABSTRACT Despite a short history since its first isolation, Akkermansia muciniphila has been extensively studied in relation to its effects on human metabolism. A recent human intervention study also demonstrated that the bacterium is safe… read more here.
Keywords: akkermansia muciniphila; bacterium; akkermansia; role akkermansia ... See more keywords
Akkermansia muciniphila upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2110639
Abstract: ABSTRACT The commensal bacteria that make up the gut microbiota impact the health of their host on multiple levels. In particular, the interactions taking place between the microbe-associated molecule patterns (MAMPs) and pattern recognition receptors… read more here.
Keywords: tifa; adp heptose; akkermansia muciniphila; genes involved ... See more keywords
Green Tea Encourages Growth of Akkermansia muciniphila.
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DOI: 10.1089/jmf.2019.4662
Abstract: Trillions of microorganisms reside in the hosts' gut. Since diverse activities of gut microbiota affect the hosts' health status, maintenance of gut microbiota is important for maintaining human health. Green tea (GT) has multiple beneficial… read more here.
Keywords: green tea; growth akkermansia; akkermansia muciniphila; gut microbiota ... See more keywords
Akkermansia muciniphila attenuates LPS-induced acute kidney injury by inhibiting TLR4/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2022 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnac103
Abstract: Acute kidney injury (AKI) is a global public health hazard with high morbidity and mortality. Sepsis accounts for nearly half of all causes of AKI. Scientists have made a great effort to explore effective therapeutic… read more here.
Keywords: akkermansia muciniphila; acute kidney; kidney; kidney injury ... See more keywords