Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer
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DOI: 10.1007/s13402-017-0351-7
Abstract: PurposeAldo-keto reductases (including AKR1B1 and AKR1B10) constitute a family of oxidoreductases that have been implicated in the pathophysiology of diabetes and cancer, including colorectal cancer (CRC). Available data indicate that, despite their similarities in structure… read more here.
Keywords: keto reductases; colorectal cancer; expression; akr1b1 akr1b10 ... See more keywords
Overexpression and enhanced specific activity of aldoketo reductases (AKR1B1 & AKR1B10) in human breast cancers.
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DOI: 10.1016/j.breast.2016.11.003
Abstract: The incidence of breast cancer in India is on the rise and is rapidly becoming the primary cancer in Indian women. The aldoketo reductase (AKR) family has more than 190 proteins including aldose reductase (AKR1B1)… read more here.
Keywords: breast; specific activity; akr1b1 akr1b10; cancer ... See more keywords
AKR1B1 as a Prognostic Biomarker of High-Grade Serous Ovarian Cancer
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DOI: 10.3390/cancers14030809
Abstract: Simple Summary We evaluated the levels of AKR1B1 and AKR1B10 in 99 patients with high-grade serous ovarian cancer and their association with clinicopathological characteristics, survival, and response to chemotherapy. An immunohistochemical analysis showed that higher… read more here.
Keywords: high grade; grade serous; ovarian cancer; akr1b1 akr1b10 ... See more keywords