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Demethoxycurcumin mediated targeting of MnSOD leading to activation of apoptotic pathway and inhibition of Akt/NF‐&kgr;B survival signalling in human glioma U87 MG cells

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Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.02.020

Abstract: ABSTRACT Earlier, we reported that Demethoxycurcumin (DMC) suppressed the growth of human glioma U87 MG cells by downregulation of Bcl‐2 expression. In the present work, we investigated the DMC induced reactive oxygen species (ROS) mediated… read more here.

Keywords: u87 cells; inhibition; activation; mnsod ... See more keywords