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Published in 2019 at "Nature immunology"
DOI: 10.1038/s41590-019-0376-3
Abstract: B cell antigen receptor (BCR) and CD40 signaling are rewired in germinal center (GC) B cells (GCBCs) to optimize selection for high-affinity B cells. In GCBC, BCR signals are constrained, but the mechanisms are not…
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Keywords:
germinal center;
bcr;
center cells;
akt kinase ... See more keywords
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Published in 2019 at "Cellular reprogramming"
DOI: 10.1089/cell.2018.0054
Abstract: The many circadian clock genes build up a network structure that controls physiological processes, such as the sleep cycle, metabolism, and hormone secretion. Cryptochrome 1 (CRY1), as one of the critical circadian proteins, is closely…
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Keywords:
cry1;
kinase;
extracellular signal;
differentiation ... See more keywords
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Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz747.0342
Abstract: The type 2 diabetic mellitus (DM2) induces the myocardial dysfunctions, the impairment of beta-adrenergic regulations and the alterations of energy homeostasis and apoptotic processes in the myocardium are the main causes of diabetic cardiomyopathy. Metformin…
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Keywords:
kinase;
effect;
akt kinase;
diabetic rats ... See more keywords
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Published in 2021 at "Viruses"
DOI: 10.3390/v13050896
Abstract: Arthropod-borne flaviviruses, such as Zika virus (ZIKV), Usutu virus (USUV), and West Nile virus (WNV), are a growing cause of human illness and death around the world. Presently, no licensed antivirals to control them are…
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Keywords:
akt;
flavivirus replication;
kinase intervenes;
akt kinase ... See more keywords