Sodium arsenite-induced cardiovascular and renal dysfunction in rat via oxidative stress and protein kinase B (Akt/PKB) signaling pathway
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DOI: 10.1080/13510002.2017.1308910
Abstract: ABSTRACT Objectives: Arsenic is a ubiquitous element that is widely distributed in the environment to which man and animals are exposed. Cardiovascular disease is one of the aftermaths of chronic arsenic exposure-related morbidity and mortality.… read more here.
Keywords: sodium arsenite; akt pkb; exposure; protein kinase ... See more keywords
IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Anti-inflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages
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DOI: 10.2174/1573406413666170922095011
Abstract: BACKGROUND 3,3'-Diindolylmethane (DIM) is a condensation product of indole-3-carbinol, a glucosinolate naturally occurring in Brassica genus vegetables. The antiinflammatory properties of DIM through the inhibition of NF-κB, as well as its ameliorating effects on glucose… read more here.
Keywords: akt pkb; irs py612; effect; pkb pt308 ... See more keywords
CDKL3 promotes osteosarcoma progression by activating Akt/PKB
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DOI: 10.26508/lsa.202000648
Abstract: This study demonstrates that CDKL3 regulates Akt activation and its downstream targets to promote OS progression, creating a therapeutically targetable vulnerability in treatment of OS. Osteosarcoma (OS) is a primary malignant bone neoplasm with high… read more here.
Keywords: akt activation; akt pkb; progression; cdkl3 ... See more keywords