Macrolactin F inhibits RANKL‐mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP‐2/smad/Akt/Runx2 signaling pathway
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DOI: 10.1016/j.ejphar.2017.09.015
Abstract: Abstract The balance between bone formation and bone resorption is maintained by osteoblasts and osteoclasts. In the current study, macrolactin F (MF) was investigated for novel biological activity on the receptor activator of nuclear factor‐&kgr;B… read more here.
Keywords: akt; akt runx2; bmp smad; bone ... See more keywords