High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells.
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DOI: 10.1016/j.lfs.2020.117914
Abstract: Hyperglycemia and oxidative stress are the primary stressors that elicit mitochondria specific cell stress in diabetes. Here we hypothesized that elevated level of ROS in high glucose (HG) environment, trigger mitochondrial stress by damaging mitochondrial… read more here.
Keywords: tuberin mtor; erk1 akt; akt tuberin; tuberin ... See more keywords