Articles with "akt1 pathway" as a keyword



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High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-14072-x

Abstract: The study investigated the role of Akt1 through the cardioprotection of high-concentration hydrogen (HCH). C57BL/6 mice were randomly divided into the following groups: sham, I/R, I/R + HCH, I/R + HCH + LY294002 (PI3K inhibitor), I/R + HCH + wortmannin (PI3K inhibitor), I/R + LY294002, and I/R + wortmannin.… read more here.

Keywords: high concentration; hydrogen; hch; reperfusion ... See more keywords
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HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway

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Published in 2017 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2017.00420

Abstract: Glioblastoma is the most common malignant tumor in central nervous system (CNS), and it is still insurmountable and has a poor prognosis. The proliferation and survival mechanism of glioma cells needs to be explored further… read more here.

Keywords: hax; hax protects; apoptosis; protects glioblastoma ... See more keywords