Is 5-ALA fluorescence of cerebral metastases a prognostic factor for local recurrence and overall survival?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-03066-y
Abstract: Background5-Aminolevulinic acid (5-ALA) fluorescence-guided resection technique was first introduced for malignant glioma. However, the impact of the 5-ALA fluorescence behaviour of cerebral metastases is still unclear. Aim of this study was to determine the impact… read more here.
Keywords: ala; ala fluorescence; cerebral metastases; fluorescence ... See more keywords
Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Neuro-Oncology Practice"
DOI: 10.1093/nop/npad025
Abstract: 5-aminolevulinic acid (5-ALA) fluorescence-guided resection increases the percentage of complete CNS tumor resections and improves the progression-free survival of IDH-wildtype glioblastoma patients. A small subset of IDH-wildtype glioblastoma show no 5-ALA fluorescence. An explanation for… read more here.
Keywords: idh wildtype; fluorescence; glioblastoma; ala fluorescence ... See more keywords
5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)—Experience at Two Specialized Centers
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13112540
Abstract: Simple Summary 5-aminolevulinic acid (5-ALA) is administered orally before brain tumor surgery to improve intraoperative visualization of tumor tissue. In comparison to most of the aggressive high-grade gliomas, only a few low-grade gliomas (LGG) demonstrate… read more here.
Keywords: surgery; ala fluorescence; grade; fluorescence ... See more keywords