Mesoscopic study of polymeric micelles with multiple lower critical solution temperatures: Micellar phase control by temperature effect
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2018.07.021
Abstract: Abstract By means of the construction of thermoresponsive triblock poly(N-isopropylacrylamide)-b-poly(N-methacryloylalanine methyl ester)-b-poly(N-acryloyl-4-trans-hydroxy- L -proline methyl ester), P(NIPAM)-b-P(MA-Ala-OMe)-b-P(A-Hyp-OMe) in an aqueous environment it is shown by simulations of dissipative particle dynamics that due to the different… read more here.
Keywords: micellar phase; temperature; ala ome; hyp ome ... See more keywords
A new GSH-responsive prodrug of 5-aminolevulinic acid for photodiagnosis and photodynamic therapy of tumors.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111582
Abstract: 5-Aminolevulinic acid (5-ALA) and its two ester derivatives (5-ALA-OMe and 5-ALA-OHex) have been approved for photodiagnosis and photodynamic therapy (PDT) of tumors in the clinical. However, their pharmacological activities are limited by their instability under… read more here.
Keywords: ala ome; aminolevulinic acid; photodynamic therapy; photodiagnosis photodynamic ... See more keywords
Matrix-isolation vibrational circular dichroism spectroscopy in structural studies of peptides: Conformational landscape of the Ac(-Ala)1–4-OMe depsipeptide series
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Spectroscopy"
DOI: 10.1016/j.jms.2018.06.005
Abstract: Abstract Depsipeptides are naturally occurring peptide analogues containing ester functionalities and are in the focus of numerous pharmaceutical researches and clinical studies owing to their enzyme inhibitor properties and cytotoxic activity against human tumor cell… read more here.
Keywords: depsipeptide series; conformational landscape; ala ome; ome depsipeptide ... See more keywords