Clinical uses of 5-aminolaevulinic acid in photodynamic treatment and photodetection of cancer: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.06.008
Abstract: ALA-mediated Photodynamic Therapy (ALA-PDT) is one of the most promising fields in Photodynamic therapy (PDT) research for cancer treatment. 5-aminolaevulinic acid (ALA) is the prodrug of the photosensitiser Protoporphyrin IX (PpIX). After ALA administration, cells… read more here.
Keywords: ala pdt; ala; treatment; clinical uses ... See more keywords
Development of a novel Schiff base derivative for enhancing the anticancer potential of 5-aminolevulinic acid-based photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2017.10.014
Abstract: 5-Aminolevulinic acid (ALA), a precursor of protoporphyrin IX (PpIX), is now widely used for photodynamic diagnosis (ALA-PDD) and photodynamic therapy (ALA-PDT) of various cancers. Recently, we found that treatment of cancer cells with the Schiff… read more here.
Keywords: ala pdt; aminolevulinic acid; photodynamic therapy; ala ... See more keywords
Effects of ALA-PDT on biofilm structure, virulence factor secretion, and QS in Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2018 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2018.07.005
Abstract: AIM To investigate the effects of ALA-PDT on biofilm structure, virulence factor secretion, and quorum sensing (QS) in Pseudomonas aeruginosa. MATERIALS AND METHODS We used confocal laser scanning microscopy (CLSM), an XTT assay, scanning electron… read more here.
Keywords: ala pdt; secretion; biofilm; virulence factor ... See more keywords
Perspective clinical study on effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating condylomata acuminata in pregnancy.
Sign Up to like & getrecommendations! Published in 2019 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2018.11.012
Abstract: OBJECTIVE To observe the clinical efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating vulval condylomata acuminata (CA) in pregnancy. METHODS The clinical efficacies of ALA-PDT on 16 cases of CA in pregnancy as well… read more here.
Keywords: ala pdt; aminolevulinic acid; photodynamic therapy; pregnancy ... See more keywords
Comparison of efficacy, adverse effects and costs between 20% ALA-PDT and 10% ALA-PDT for the treatment of actinic keratosis in Chinese patients.
Sign Up to like & getrecommendations! Published in 2019 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2019.101605
Abstract: BACKGROUND 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) is a reliable treatment for actinic keratosis (AK), and the concentration of ALA for this treatment is 20% in most studies, but it was found that 10% ALA… read more here.
Keywords: ala pdt; ala; efficacy adverse; treatment ... See more keywords
Treatment of Hyperkeratotic Vulvar Lichen Sclerosus with combination of holmium laser therapy and ALA-PDT:case report.
Sign Up to like & getrecommendations! Published in 2020 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2020.101762
Abstract: A 72-year old woman who has a history of refractory vulvar lichen sclerosus(VLS) was treated with ALA-PDT for 3 times every other week,then holmium laser and ALA-PDT were combined to treat the same areas at… read more here.
Keywords: ala pdt; therapy; pdt; holmium laser ... See more keywords
5-Aminolevulinic acid photodynamic therapy for early-stage lip squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2021.102321
Abstract: BACKGROUND Lip skin squamous cell carcinoma (SCC) removed by surgery may cause lip dysfunction due to the special location. ALA-PDT (5-Aminolevulinic acid photodynamic therapy) is a minimally invasive treatment for superficial SCC in situ. However,… read more here.
Keywords: ala pdt; lip; cell carcinoma; squamous cell ... See more keywords
5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: a case report.
Sign Up to like & getrecommendations! Published in 2021 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2021.102387
Abstract: Erosive adenomatosis of the nipple (EAN) is a very uncommon, benign neoplasm that involves the nipple. Generally, complete surgical excision is the main treatment, and we can take alternative therapeutic methods such as Mohs micrographic… read more here.
Keywords: ala pdt; adenomatosis nipple; photodynamic therapy; erosive adenomatosis ... See more keywords
Predictors of therapeutic efficacy of 5-aminolevulinic acid-based photodynamic therapy in human prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2021.102452
Abstract: BACKGROUND Photodynamic therapy (PDT) is a minimally invasive cancer therapy. However, its therapeutic efficacy for prostate cancer is not yet fully understood. In this study, the predictors of therapeutic efficacy of 5-aminolevulinic acid-based PDT (ALA-PDT)… read more here.
Keywords: ala pdt; therapy; pdt; prostate cancer ... See more keywords
Remodeling lymphatic vessels in intrinsically aged skin on SKH-1 mouse using low dose 5-aminolevulinic acid photodynamic therapy via VEGF-C/VEGFR3 pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2022.102851
Abstract: BACKGROUND Decline of lymphatic vessel (LV) density and function in intrinsically aged skin leads to harmful substances accumulation and fluid imbalance. Whether it will be improved by low dose ALA-PDT needs to be investigated. AIMS… read more here.
Keywords: intrinsically aged; aged skin; ala pdt; low dose ... See more keywords
PD-L1 blockade potentiates the antitumor effects of ALA-PDT and optimizes the tumor microenvironment in cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2061396
Abstract: ABSTRACT Immune checkpoint blockade (ICB) is a powerful oncologic treatment modality for a wide variety of human malignancies, but the patient response rate to this treatment remains low, especially in patients with cutaneous squamous cell… read more here.
Keywords: effects ala; cell; antitumor effects; blockade ... See more keywords