Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo.
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DOI: 10.1021/acsinfecdis.0c00545
Abstract: The development of antimicrobial compounds is now regarded as an urgent problem. Antimicrobial peptides (AMPs) have great potential to become novel antimicrobial drugs. Feleucin-K3 is an α-helical cationic AMP isolated from the skin secretion of… read more here.
Keywords: ala substitution; antimicrobial antibiofilm; key site; substitution ... See more keywords