Synthesis and Bioactivity of the Alanyl Phosphonamidate Stereoisomers Derived from a Butyrophilin Ligand.
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DOI: 10.1021/acsmedchemlett.9b00153
Abstract: Aryloxy phosphonamidate derivatives of a butyrophilin 3A1 ligand are stimulants of Vγ9 Vδ2 T cells. However, when bonded to an aryl ester and an amine, the phosphorus is stereogenic, and past compounds were studied as… read more here.
Keywords: phosphonamidate; bioactivity alanyl; ligand; synthesis bioactivity ... See more keywords