Hematopoietic progenitor cell liabilities and alarmins S100A8/A9‐related inflammaging associate with frailty and predict poor cardiovascular outcomes in older adults
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DOI: 10.1111/acel.13545
Abstract: Frailty affects the physical, cognitive, and social domains exposing older adults to an increased risk of cardiovascular disease and death. The mechanisms linking frailty and cardiovascular outcomes are mostly unknown. Here, we studied the association… read more here.
Keywords: older adults; alarmins s100a8; progenitor; poor cardiovascular ... See more keywords
Pathogenic roles of neutrophil‐derived alarmins (S100A8/A9) in heart failure: From molecular mechanisms to therapeutic insights
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DOI: 10.1111/bph.15998
Abstract: An excessive neutrophil count is recognized as a valuable predictor of inflammation and is associated with a higher risk of adverse cardiac events in patients with heart failure. Our understanding of the effectors used by… read more here.
Keywords: heart failure; neutrophil derived; derived alarmins; alarmins s100a8 ... See more keywords