Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol
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DOI: 10.7554/elife.82269
Abstract: PCSK9 negatively regulates low-density lipoprotein receptor (LDLR) abundance on the cell surface, leading to decreased hepatic clearance of LDL particles and increased levels of plasma cholesterol. We previously identified SURF4 as a cargo receptor that… read more here.
Keywords: surf4fl alb; surf4; alb cre; mice ... See more keywords