Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland
Sign Up to like & getrecommendations! Published in 2020 at "Infection"
DOI: 10.1007/s15010-020-01475-8
Abstract: Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In this study, we report the emergence of FKS-mutant Candida albicans/glabrata in Switzerland and provide the… read more here.
Keywords: emerging echinocandin; albicans glabrata; candida albicans; glabrata switzerland ... See more keywords
Moonlighting proteins induce protection in a mouse model against Candida species.
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DOI: 10.1016/j.micpath.2018.08.024
Abstract: In recent years, C. albicans and C. glabrata have been identified as the main cause of candidemia and invasive candidiasis in hospitalized and immunocompromised patients. In order to colonize the human host, these fungi express… read more here.
Keywords: albicans glabrata; protection; candida species; cwp ... See more keywords
EUCAST in vitro activity of Ibrexafungerp (SCY-078) against C. auris isolates; comparison with activity against C. albicans and C. glabrata and with that of six comparators.
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DOI: 10.1128/aac.02136-19
Abstract: Ibrexafungerp (SCY-078) is a novel first-in-class antifungal agent targeting the glucan synthase. C. auris is an emerging multidrug resistant species that has caused outbreaks on five continents. We investigated the in vitro activity of ibrexafungerp… read more here.
Keywords: scy 078; activity; albicans glabrata; ibrexafungerp scy ... See more keywords
Relative Abundances of Candida albicans and Candida glabrata in In Vitro Coculture Biofilms Impact Biofilm Structure and Formation
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DOI: 10.1128/aem.02769-17
Abstract: ABSTRACT Candida is a member of the normal human microbiota and often resides on mucosal surfaces such as the oral cavity or the gastrointestinal tract. In addition to their commensality, Candida species can opportunistically become… read more here.
Keywords: albicans glabrata; albicans candida; formation; candida albicans ... See more keywords