Articles with "albumin" as a keyword



Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial.

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Published in 2025 at "JAMA surgery"

DOI: 10.1001/jamasurg.2025.1683

Abstract: Importance Acute kidney injury (AKI) after cardiac surgery is a common and serious complication. Protein loading appears nephroprotective; thus, continuous hyperoncotic albumin infusion may impact AKI following high-risk cardiac surgery. Objective To evaluate the effect… read more here.

Keywords: surgery; risk; cardiac surgery; infusion ... See more keywords

Light‐Triggered Retention and Cascaded Therapy of Albumin‐Based Theranostic Nanomedicines to Alleviate Tumor Adaptive Treatment Tolerance

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Published in 2018 at "Advanced Functional Materials"

DOI: 10.1002/adfm.201707291

Abstract: Human serum albumin (HSA)‐based nanomedicines modified with diazirine and loaded with indocyanine green (ICG) and tirapazamine (TPZ) , are fabricated to increase the accumulation efficiency of chemo‐drugs and reinforce their therapeutic efficacy through cascaded synergistic… read more here.

Keywords: therapy albumin; light triggered; cascaded therapy; retention cascaded ... See more keywords

Ultra-small Albumin Templated Gd/Ru Composite Nanodots for In Vivo Dual modal MR/Thermal Imaging Guided Photothermal Therapy.

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Published in 2018 at "Advanced healthcare materials"

DOI: 10.1002/adhm.201800322

Abstract: Multifunctional theranostic nanoagents which realize precise diagnosis and treatment of tumors are attracting increasing interests in recent years. However, efficient and controlled synthesis of ultra-small noble metal nanoagents remains a challenge. Here, monodisperse Gd/Ru@BSA nanodots… read more here.

Keywords: small albumin; albumin templated; imaging; albumin ... See more keywords

Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202500851

Abstract: This work aimed to investigate the interaction of a self‐assembled myristic acid‐conjugated quetiapine nanosuspension (QMN) with human serum albumin and its overturning effect on QMN's long‐acting performance. Albumin corona formation modified the physicochemical properties and… read more here.

Keywords: long acting; conjugated quetiapine; qmn; acid conjugated ... See more keywords

Conjugating Hemoglobin and Albumin by Strain‐Promoted Azide‐ Alkyne Cycloaddition

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Published in 2024 at "ChemBioChem"

DOI: 10.1002/cbic.202400206

Abstract: A one‐to‐one conjugate of cross‐linked human hemoglobin and human serum albumin results from a strain‐promoted alkyne‐azide cycloaddition (SPAAC) of the modified proteins. Additions of a strained alkyne‐substituted maleimide to the Cys‐34 thiol of human serum… read more here.

Keywords: hemoglobin albumin; albumin strain; albumin; strain promoted ... See more keywords

Structural investigations of stereoselective profen binding by equine and leporine serum albumins.

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Published in 2020 at "Chirality"

DOI: 10.1002/chir.23162

Abstract: Serum albumin, the most abundant transport protein of mammalian blood, interacts with various nonsteroidal anti-inflammatory drugs (NSAIDs) affecting their disposition, metabolism, and excretion. A big group of chiral NSAIDs transported by albumin, profens, is created… read more here.

Keywords: leporine serum; serum; site; equine leporine ... See more keywords

Prognostic impact of follow-up serum albumin after acute myocardial infarction.

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Published in 2021 at "ESC heart failure"

DOI: 10.1002/ehf2.13640

Abstract: AIMS Previous studies have suggested that low serum albumin (LSA) at admission for acute myocardial infarction (AMI) is associated with adverse in-hospital outcomes. The aim of this study was to investigate whether LSA in the… read more here.

Keywords: prognostic impact; ami; serum albumin; albumin ... See more keywords

Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis

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Published in 2017 at "Hepatology"

DOI: 10.1002/hep.28897

Abstract: Albumin is a potent scavenger of reactive oxygen species (ROS). However, modifications in albumin structure may reduce its antioxidant properties and modulate its immune‐regulatory functions. We examined alterations in circulating albumin in severe alcoholic hepatitis… read more here.

Keywords: severe alcoholic; stress; albumin; sah ... See more keywords

Assessment of the Toxic Effect of Zinc Oxide Nanoparticles on Brain, Kidney and Spleen of Adult Male Albino Rats and Possible Protective Role of Copper (II) Albumin Complex

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Published in 2025 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70530

Abstract: The present study aimed to assess the toxic effect of sub chronic administration of zinc oxide nanoparticles (ZnO‐NPs) on brain, kidney and spleen of adult male rats and to assess the possible protective role of… read more here.

Keywords: albumin complex; albumin; zno nps; brain kidney ... See more keywords

Intracellular transcytosis of albumin in glomerular endothelial cells after endocytosis through caveolae

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Published in 2017 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.25817

Abstract: We previously described albumin endocytosis through caveolae in human renal glomerular endothelial cells (HRGECs). This suggested a new albumin transcytosis pathway, in addition to the fenestral pathway. As a next step, we investigated albumin transcytosis… read more here.

Keywords: caveolae; glomerular endothelial; endocytosis; endothelial cells ... See more keywords

Characterization of binding by repaglinide and nateglinide with glycated human serum albumin using high‐performance affinity microcolumns

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Published in 2022 at "Journal of Separation Science"

DOI: 10.1002/jssc.202200686

Abstract: High‐performance affinity microcolumns were used to characterize binding by the anti‐diabetic drugs repaglinide and nateglinide with normal and glycated forms of human serum albumin. The microcolumns contained only nmol amounts of protein and provided a… read more here.

Keywords: performance affinity; repaglinide nateglinide; high performance; albumin ... See more keywords