Light‐Triggered Retention and Cascaded Therapy of Albumin‐Based Theranostic Nanomedicines to Alleviate Tumor Adaptive Treatment Tolerance
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201707291
Abstract: Human serum albumin (HSA)‐based nanomedicines modified with diazirine and loaded with indocyanine green (ICG) and tirapazamine (TPZ) , are fabricated to increase the accumulation efficiency of chemo‐drugs and reinforce their therapeutic efficacy through cascaded synergistic… read more here.
Keywords: therapy albumin; light triggered; cascaded therapy; retention cascaded ... See more keywords
Ultra-small Albumin Templated Gd/Ru Composite Nanodots for In Vivo Dual modal MR/Thermal Imaging Guided Photothermal Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201800322
Abstract: Multifunctional theranostic nanoagents which realize precise diagnosis and treatment of tumors are attracting increasing interests in recent years. However, efficient and controlled synthesis of ultra-small noble metal nanoagents remains a challenge. Here, monodisperse Gd/Ru@BSA nanodots… read more here.
Keywords: small albumin; albumin templated; imaging; albumin ... See more keywords
Structural investigations of stereoselective profen binding by equine and leporine serum albumins.
Sign Up to like & getrecommendations! Published in 2020 at "Chirality"
DOI: 10.1002/chir.23162
Abstract: Serum albumin, the most abundant transport protein of mammalian blood, interacts with various nonsteroidal anti-inflammatory drugs (NSAIDs) affecting their disposition, metabolism, and excretion. A big group of chiral NSAIDs transported by albumin, profens, is created… read more here.
Keywords: leporine serum; serum; site; equine leporine ... See more keywords
Prognostic impact of follow-up serum albumin after acute myocardial infarction.
Sign Up to like & getrecommendations! Published in 2021 at "ESC heart failure"
DOI: 10.1002/ehf2.13640
Abstract: AIMS Previous studies have suggested that low serum albumin (LSA) at admission for acute myocardial infarction (AMI) is associated with adverse in-hospital outcomes. The aim of this study was to investigate whether LSA in the… read more here.
Keywords: prognostic impact; ami; serum albumin; albumin ... See more keywords
Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28897
Abstract: Albumin is a potent scavenger of reactive oxygen species (ROS). However, modifications in albumin structure may reduce its antioxidant properties and modulate its immune‐regulatory functions. We examined alterations in circulating albumin in severe alcoholic hepatitis… read more here.
Keywords: severe alcoholic; stress; albumin; sah ... See more keywords
Intracellular transcytosis of albumin in glomerular endothelial cells after endocytosis through caveolae
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25817
Abstract: We previously described albumin endocytosis through caveolae in human renal glomerular endothelial cells (HRGECs). This suggested a new albumin transcytosis pathway, in addition to the fenestral pathway. As a next step, we investigated albumin transcytosis… read more here.
Keywords: caveolae; glomerular endothelial; endocytosis; endothelial cells ... See more keywords
Characterization of binding by repaglinide and nateglinide with glycated human serum albumin using high‐performance affinity microcolumns
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Separation Science"
DOI: 10.1002/jssc.202200686
Abstract: High‐performance affinity microcolumns were used to characterize binding by the anti‐diabetic drugs repaglinide and nateglinide with normal and glycated forms of human serum albumin. The microcolumns contained only nmol amounts of protein and provided a… read more here.
Keywords: performance affinity; repaglinide nateglinide; high performance; albumin ... See more keywords
Albumin roles in developing anticancer compounds
Sign Up to like & getrecommendations! Published in 2021 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-021-02748-z
Abstract: Albumin is an abundant protein in nature with several biological functions. In the human body, both in health and in illness, its transport function is highlighted by the binding to medicinal drugs and consequent distribution… read more here.
Keywords: albumin; roles developing; chemistry; developing anticancer ... See more keywords
Unveiling the molecular mechanisms underpinning biorecognition of early-glycated human serum albumin and receptor for advanced glycation end products
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02674-w
Abstract: Serum levels of early-glycated albumin are significantly increased in patients with diabetes mellitus and may play a role in worsening inflammatory status and sustaining diabetes-related complications. To investigate possible pathological recognition involving early-glycated albumin and… read more here.
Keywords: affinity; early glycated; serum; end products ... See more keywords
The nonlinear association between albumin levels and risk of noninvasive fungal rhinosinusitis
Sign Up to like & getrecommendations! Published in 2022 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-022-07325-7
Abstract: The preoperative diagnosis of noninvasive fungal rhinosinusitis (NIFRS) is inaccurate, and biomarkers to assist the diagnosis are urgently needed. We aimed to evaluate the relationship between albumin levels and NIFRS to assist in early diagnosis.… read more here.
Keywords: albumin; noninvasive fungal; levels nifrs; association albumin ... See more keywords
Control releasing 5-aminosalicylic acid using pH-sensitive hydrogel with novel albumin cross-linker
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"
DOI: 10.1007/s10847-018-0863-4
Abstract: Intelligent drug delivery systems are growing and changing too fast, these systems usually show a proper response at the proper time to one or several environmental factors. In the current research a biodegradable drug delivery… read more here.
Keywords: hydrogel; aminosalicylic acid; cross linker; albumin ... See more keywords