Deafness‐Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205993
Abstract: The ankle‐link complex (ALC) consists of USH2A, WHRN, PDZD7, and ADGRV1 and plays an important role in hair cell development. At present, its architectural organization and signaling role remain unclear. By establishing Adgrv1 Y6236fsX1 mutant… read more here.
Keywords: deafness associated; alc; stability; mutation ... See more keywords
Structural Engineering Enabled Bimetallic (Ti1- y Nby )2 AlC Solid Solution Structure for Efficient Electromagnetic Wave Absorption in Gigahertz.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300119
Abstract: Microstructures play a critical role to influence the polarization behavior of dielectric materials, which determines the electromagnetic response ability in gigahertz. However, the relationship between them, especially in the solid-solution structures is still absent. Herein,… read more here.
Keywords: ti1; alc; solution; absorption ... See more keywords
A fuzzy spatial description logic for the semantic web
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ambient Intelligence and Humanized Computing"
DOI: 10.1007/s12652-020-01864-9
Abstract: Spatial information is a critical feature in a large number of application domains. Spatial information, however, is often not crisp but with the nature of imprecision and fuzziness. As the increasing requirements of spatial applications,… read more here.
Keywords: mathcal alc; description logic; alc; semantic web ... See more keywords
Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson’s disease mouse model: Endothelial and microglial effects
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.03.015
Abstract: Parkinson's disease (PD) is a progressive motor disease with clinical features emerging due to degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc), which project to the caudate putamen (CPu) where they release… read more here.
Keywords: mptp; mptp induced; alc; pathology ... See more keywords
Acetyl-L-Carnitine Induces Autophagy to Promote Mouse Spermatogonia Cell Recovery after Heat Stress Damage
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/8871328
Abstract: Acetyl-L-carnitine (ALC) is an effective substrate for mitochondrial energy metabolism and is known to prevent neurodegeneration and attenuate heavy metal-induced injury. In this study, we investigated the function of ALC in the recovery of mouse… read more here.
Keywords: heat stress; group; alc; stress ... See more keywords
Absolute Lymphocyte Count as an Independent Prognostic Factor in Metastatic Breast Cancer: A Retrospective Study
Sign Up to like & getrecommendations! Published in 2022 at "Oncology"
DOI: 10.1159/000526963
Abstract: Introduction: Recently, absolute lymphocyte count (ALC) and neutrophil-to-lymphocyte ratio (NLR) have been reported to be prognostic and/or predictive factors in breast cancer. However, most of the investigations on the relationship between systemic inflammatory markers and… read more here.
Keywords: independent prognostic; breast cancer; absolute lymphocyte; alc ... See more keywords
Regeneration of sciatic nerve injury through nanofiber neural guidance channels containing collagen hydrogel and acetyl L carnitine: An in vitro and in vivo study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bioactive and Compatible Polymers"
DOI: 10.1177/08839115221137654
Abstract: Unlike the central nervous system (CNS), peripheral nervous system (PNS) injuries are partially repairable. Nerve guidance channels (NGCs) have been shown to improve the level of nerve repair after injury. In the present study, we… read more here.
Keywords: hydrogel; collagen; nerve; alc ... See more keywords
Dynamics of Leukocyte Subpopulations Reconstitution Predict Infection Propensity in a Multiethnic Real World Cohort Treated with Anti-CD19 CAR-T Cell Therapy (Axicabtagene-Ciloleucel)
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-139533
Abstract: Background: Adoptive immunotherapy using CD19-targeted Chimeric Antigen Receptor T-cells (CAR-T) has revolutionized the treatment of relapsed/refractory diffuse large B-cell lymphoma (DLBCL). We have demonstrated the efficacy of FDA-approved axicabtagene ciloleucel (Yescarta) in a multiethnic New… read more here.
Keywords: infection group; infection; group; reconstitution ... See more keywords
Absolute Lymphocyte Count As a Predictor of Safety and Efficacy Post CART for Multiple Myeloma and B Cell Malignancies
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-205978
Abstract: Background: Absolute lymphocyte count (ALC) has previously been investigated as a prognostic factor for patients with relapsed/refractory (R/R) multiple myeloma due to its association with host immune status and the ability to successfully manufacture autologous… read more here.
Keywords: crs icans; infusion; car; cell ... See more keywords
The Impact of the Absolute Lymphocyte Count before Anti-T-Lymphocyte Globulin (ATLG) Administration on Transplant Outcomes in Matched Unrelated Peripheral Blood Stem Cell Allogeneic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-211102
Abstract: Background: Data on optimal ATLG dosing in MUD-PBSC-allo-SCT is limited. Conventional weight-based dosing may excessively deplete T-cells and lead to unfavorable outcomes. ALC-based dosing on ATLG administration day has been proposed as an alternative. We… read more here.
Keywords: administration; low alc; high alc; alc group ... See more keywords
Evaluating the Impact of Absolute Lymphocyte Count on Outcomes in ATG Containing Haploidentical HSCT for Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-212406
Abstract: Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely performed as a treatment for acute myeloid leukemia (AML). In HSCT, graft-versus-host disease (GVHD) remains a critical issue associated with mortality, and several drugs are used… read more here.
Keywords: atg administration; hsct; alc; haploidentical hsct ... See more keywords