ALC1 knockdown enhances cisplatin cytotoxicity of esophageal squamous cell carcinoma cells by inhibition of glycolysis through PI3K/Akt pathway.
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DOI: 10.1016/j.lfs.2019.116679
Abstract: AIMS Amplified in liver cancer 1 gene (ALC1), a recently identified oncogene, was reported to be overexpressed in esophageal cancer cell lines and identified as a target oncogene in esophageal cancer pathogenesis. However, little literature… read more here.
Keywords: cisplatin cytotoxicity; glycolysis; alc1 knockdown; pi3k akt ... See more keywords