Anaplastic Large Cell Lymphoma: Contemporary Concepts and Optimal Management.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer treatment and research"
DOI: 10.1007/978-3-319-99716-2_6
Abstract: Anaplastic Large Cell Lymphomas (ALCL) are clinically aggressive and pathologically distinct lymphoid neoplasms that originate from a mature post-thymic T-cell. The contemporary World Health Organization (WHO) Classification of Haematologic Malignancies recognizes two distinct subtypes of… read more here.
Keywords: alcl; alk positive; management; large cell ... See more keywords
A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-01088-y
Abstract: Aberrant activation of NF-κB is the most striking oncogenic mechanism in B-cell lymphoma; however, its role in anaplastic large cell lymphomas (ALCL) has not been fully established and its activation mechanism(s) remain unclear. Using ALCL… read more here.
Keywords: alk; alcl; pathway; activation ... See more keywords
How I Diagnose Anaplastic Large Cell Lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqab012
Abstract: OBJECTIVES This review describes our approach to the diagnosis of all 4 anaplastic large cell lymphoma (ALCL) entities. METHODS ALCLs are a group of CD30-positive mature T-cell lymphomas with similar morphologic and phenotypic characteristics but… read more here.
Keywords: alcl; large cell; cell; anaplastic large ... See more keywords
Anaplastic Large Cell Lymphoma Manifesting as Pleural Effusion in a Patient with Long-Standing Eosinophilia.
Sign Up to like & getrecommendations! Published in 2019 at "Laboratory medicine"
DOI: 10.1093/labmed/lmy035
Abstract: Anaplastic large cell lymphoma (ALCL) is a lymphoma of T-cell origin, characterized by the presence of large lymphoid cells with abundant cytoplasm and pleomorphic, often horseshoe-shaped nuclei (hallmark cells), as well as strong and uniform… read more here.
Keywords: lymphoma; alcl; large cell; cell ... See more keywords
Anaplastic large cell lymphoma in children and adolescents
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Haematology"
DOI: 10.1111/bjh.20154
Abstract: Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of… read more here.
Keywords: cell lymphoma; alcl; large cell; lymphoma ... See more keywords
How to Diagnose Anaplastic Large Cell Lymphoma on Cytological Samples? A Series with Emphasis on Diagnostic Clue and Pitfalls.
Sign Up to like & getrecommendations! Published in 2023 at "Acta cytologica"
DOI: 10.1159/000528533
Abstract: INTRODUCTION Anaplastic large cell lymphoma (ALCL) is a rare mature T-cell non-Hodgkin's lymphoma characterized by large and pleomorphic neoplastic CD30-positive T cells. ALCL includes different subtypes with different clinical and biological features: systemic ALCL, primary… read more here.
Keywords: cell; diagnosis; cytological samples; alcl ... See more keywords
MYC Expression in Systemic Anaplastic Large Cell Lymphoma: Clinicopathologic and Prognostic Features of 70 Patients
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-124556
Abstract: Background: Dysregulation of MYC has oncogenic potential. It has been reported that MYC dysregulation (gene rearrangement, increased copy number, and protein overexpression) predicts poorer prognosis in patients with diffuse large B cell lymphoma. Systemic anaplastic… read more here.
Keywords: alcl; expression; alk negative; myc expression ... See more keywords
GSK1838705a, an IGF-1R/ALK Inhibitor, Overcomes Resistance to Crizotinib in ALK-Positive ALCL
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-130063
Abstract: Anaplastic large cell lymphoma (ALCL) is a type of CD30-expressing non-Hodgkin's lymphoma (NHL), which accounts for 2% to 3% of adult non-Hodgkin's lymphoma,accounting for 15% to 30% of children with large cell lymphoma. Anaplastic lymphoma… read more here.
Keywords: crizotinib resistant; alk; alcl; alk alcl ... See more keywords
GATA3 Gene - a Potential New Biomarker Associated with Adverse Outcomes in ALK1-Negative Anaplastic Large Cell Lymphoma: Preliminary Results from a Retrospective Cohort of 80 South American Cases of Nodal Peripheral T Lymphoma
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DOI: 10.1182/blood-2020-140833
Abstract: Introduction: Nodal peripheral T-cell lymphomas (nPTCLs) comprise a heterogeneous group of mature and aggressive T-cell lymphoid malignancies, including peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS), angioimmunoblastic T-cell lymphoma (AITL) and anaplastic large cell lymphomas… read more here.
Keywords: alcl; gata3 gene; gene; cell ... See more keywords
Metagenomic analysis to identify novel infectious agents in systemic anaplastic large cell lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Infectious Agents and Cancer"
DOI: 10.1186/s13027-021-00404-0
Abstract: Systemic anaplastic large cell lymphoma (ALCL) is a rare CD30-expressing T-cell non-Hodgkin lymphoma. Risk of systemic ALCL is highly increased among immunosuppressed individuals. Because risk of cancers associated with viruses is increased with immunosuppression, we… read more here.
Keywords: lymphoma; alcl; analysis; systemic anaplastic ... See more keywords
Anaplastic large cell T-cell lymphoma: insights from cytological and immunological profiles across ten diverse cases.
Sign Up to like & getrecommendations! Published in 2024 at "Annales de biologie clinique"
DOI: 10.1684/abc.2024.1928
Abstract: While the latest WHO classification of hematological neoplasms helps refine the diagnostic criteria for anaplastic large cell lymphomas (ALCL), their diagnosis can still be challenging. This retrospective series of 10 ALCL cases illustrates the cytological… read more here.
Keywords: cell cell; cell lymphoma; alcl; cell ... See more keywords