Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice.
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DOI: 10.1016/j.neuro.2021.05.005
Abstract: Edaravone (Eda) is a radical scavenger used in clinical trials for the treatment of ischemic stroke and amyotrophic lateral sclerosis. However, how Eda exerts its neuroprotective effects remains to be elucidated. We investigated the neuroprotective… read more here.
Keywords: hippocampal neurons; alcl3 galactose; induced cognitive; cognitive impairment ... See more keywords