Industrial light at the end of the iron‐containing (group III) alcohol dehydrogenase tunnel
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2376
Abstract: There are three prominent alcohol dehydrogenases superfamilies: short‐chain, medium‐chain, and iron‐containing alcohol dehydrogenases (FeADHs). Many members are valuable catalysts for producing industrially relevant products such as active pharmaceutical intermediates, chiral synthons, biopolymers, biofuels, and secondary… read more here.
Keywords: alcohol dehydrogenases; tunnel; industrial light; alcohol ... See more keywords
A secretion‐based dual fluorescence assay for high‐throughput screening of alcohol dehydrogenases
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27677
Abstract: Alcohol dehydrogenases (ADHs) play key roles in the production of various chemical precursors that are essential in pharmaceutical and fine chemical industries. To achieve a practical application of ADHs in industrial processes, tailoring enzyme properties… read more here.
Keywords: secretion; fluorescence; dual fluorescence; based dual ... See more keywords
Cell-free biosynthesis of ω-hydroxy acids boosted by a synergistic combination of alcohol dehydrogenases.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202200397
Abstract: The activity orchestration of an unprecedented cell-free enzyme system with self-sufficient cofactor recycling enables the step-wise transformation of aliphatic diols into ω-hydroxy acids at the expense of molecular oxygen as electron acceptor. The efficiency of… read more here.
Keywords: alcohol dehydrogenases; system; cell free; hydroxy acids ... See more keywords
Alcohol dehydrogenases from Proteus mirabilis contribute to alcoholic flavor.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9642
Abstract: BACKGROUND Cheese ripening involves a complex series of metabolic reactions and numerous concomitant secondary transformations. Alcohol dehydrogenase (ADH) converts aldehydes into their corresponding alcohols, which enrich cheese aroma. RESULTS In this study, we identified five… read more here.
Keywords: dehydrogenases proteus; flavor; alcohol dehydrogenases; adh adh ... See more keywords
Alcohol Dehydrogenases with anti‐Prelog Stereopreference in Synthesis of Enantiopure Alcohols
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DOI: 10.1002/open.202100251
Abstract: Abstract Biocatalytic production of both enantiomers of optically active alcohols with high enantiopurities is of great interest in industry. Alcohol dehydrogenases (ADHs) represent an important class of enzymes that could be used as catalysts to… read more here.
Keywords: anti prelog; prelog stereopreference; alcohol dehydrogenases;
Phylogenetic and functional diversity of aldehyde-alcohol dehydrogenases in microalgae.
Sign Up to like & getrecommendations! Published in 2021 at "Plant molecular biology"
DOI: 10.1007/s11103-020-01105-9
Abstract: KEY MESSAGE The study shows the biochemical and enzymatic divergence between the two aldehyde-alcohol dehydrogenases of the alga Polytomella sp., shedding light on novel aspects of the enzyme evolution amid unicellular eukaryotes. Aldehyde-alcohol dehydrogenases (ADHEs)… read more here.
Keywords: aldehyde alcohol; phylogenetic functional; polytomella; alcohol dehydrogenases ... See more keywords
Characterisation of five alcohol dehydrogenases from Lactobacillus reuteri DSM20016
Sign Up to like & getrecommendations! Published in 2019 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2019.08.010
Abstract: Abstract Alcohol dehydrogenases convert aldehydes causing volatile aromas in cheese into corresponding alcohols. In this study, we cloned and recombinantly produced five novel ADHs from Lactobacillus reuteri DSM20016 in Escherichia coli BL21 (DE3). The resulting… read more here.
Keywords: adh adh; reuteri dsm20016; lactobacillus reuteri; alcohol dehydrogenases ... See more keywords
Improved furfural tolerance in Escherichia coli mediated by heterologous NADH-dependent benzyl alcohol dehydrogenases
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Journal"
DOI: 10.1042/bcj20210811
Abstract: While lignocellulose is a promising source of renewable sugars for microbial fermentations, the presence of inhibitory compounds in typical lignocellulosic feedstocks, such as furfural, has hindered their utilisation. In Escherichia coli, a major route of… read more here.
Keywords: alcohol dehydrogenases; escherichia coli; furfural tolerance; benzyl alcohol ... See more keywords
Structural insights into alcohol dehydrogenases catalyzing asymmetric reductions
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Biotechnology"
DOI: 10.1080/07388551.2019.1566205
Abstract: Abstract Alcohol dehydrogenases are a group of oxidoreductases that specifically use NAD(P)+ or NAD(P)H as cofactors for electron acceptance or donation and catalyze interconversion between alcohols and corresponding carbonyl compounds. In addition to their physiological… read more here.
Keywords: structural insights; dehydrogenases catalyzing; alcohol dehydrogenases; catalyzing asymmetric ... See more keywords
Characterization of Thermotoga neapolitana Alcohol Dehydrogenases in the Ethanol Fermentation Pathway
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DOI: 10.3390/biology11091318
Abstract: Simple Summary Hyperthermophilic Thermotoga spp. are promising candidates for the metabolic engineering of cellulosic ethanol producing strains. However, Thermotoga spp. are hydrogen producers, and none of them have been found to produce significant amount of… read more here.
Keywords: alcohol dehydrogenases; thermotoga spp; ethanol; ctn ... See more keywords