Prenatal alcohol exposure induced congenital heart diseases: From bench to bedside
Sign Up to like & getrecommendations! Published in 2020 at "Birth Defects Research"
DOI: 10.1002/bdr2.1743
Abstract: Alcohol consumption is increasing worldwide. Many child‐bearing‐aged women consume alcohol during pregnancy, intentionally or unintentionally, thereby increasing the potential risk for severe congenital diseases. Congenital heart disease (CHD) is the most common birth defect worldwide… read more here.
Keywords: alcohol exposure; prenatal alcohol; congenital heart; alcohol ... See more keywords
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept
Sign Up to like & getrecommendations! Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2054
Abstract: Prenatal alcohol exposure (PAE), leading to fetal alcohol spectrum disorders (FASD), is a serious public health issue in the United States and globally. Diagnosis of FASD is crucial in obtaining appropriate care, but it is… read more here.
Keywords: alcohol exposure; exposure determined; alcohol; determined baby ... See more keywords
Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23164
Abstract: Alcohol exposure during central nervous system (CNS) development can lead to fetal alcohol spectrum disorder (FASD). Human imaging studies have revealed significant white matter (WM) abnormalities linked to cognitive impairment in children with FASD; however,… read more here.
Keywords: trimester equivalent; third trimester; alcohol exposure; alcohol ... See more keywords
The alcohol‐sensitive period during early octavolateral organ development in zebrafish (Danio rerio)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24017
Abstract: Fetal alcohol exposure can cause Fetal Alcohol Spectrum Disorders (FASD), completely preventable developmental disabilities characterized by permanent birth defects. However, specific gestational timing when developing organs are most sensitive to alcohol exposure is unclear. In… read more here.
Keywords: alcohol sensitive; zebrafish danio; alcohol exposure; alcohol ... See more keywords
Effects of Acute Alcohol Exposure on Layer 5 Pyramidal Neurons of Juvenile Mice
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0571-4
Abstract: Early-onset drinking during childhood or preadolescence is a serious social problem. Yet, most of the basic neurobiological research on the acute effects of ethanol has been carried out on adult or early postnatal animals. We… read more here.
Keywords: alcohol exposure; exposure; pyramidal neurons; layer pyramidal ... See more keywords
Hippocampal neurogenesis in the C57BL/6J mice at early adulthood following prenatal alcohol exposure
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0156-4
Abstract: We examined the effect of chronic prenatal alcohol exposure (PAE) on the process of adult neurogenesis in C57BL/6J mice at early adulthood (PND 56). Pregnant mice, and their in utero litters, were exposed to alcohol,… read more here.
Keywords: prenatal alcohol; c57bl mice; neurogenesis c57bl; mice early ... See more keywords
Effects of Early Daily Alcohol Exposure on Placental Function and Fetal Growth in a Rhesus Macaque Model.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2021.07.028
Abstract: BACKGROUND Prenatal alcohol exposure is the most common cause of birth defects and intellectual disabilities and can also increase the risk of stillbirth and negatively impact fetal growth. OBJECTIVE The purpose of this study is… read more here.
Keywords: alcohol exposure; fetal growth; alcohol; blood ... See more keywords
Chronic + binge alcohol exposure promotes inflammation and alters airway mechanics in the lung.
Sign Up to like & getrecommendations! Published in 2018 at "Alcohol"
DOI: 10.1016/j.alcohol.2018.10.008
Abstract: INTRODUCTION Alcohol use disorders are major risk factors for the development of and susceptibility to acute respiratory distress syndrome. Although these risks of alcohol consumption on the lung are well described, mechanisms by which alcohol… read more here.
Keywords: inflammation; alcohol exposure; binge; alcohol ... See more keywords
Moderate prenatal alcohol exposure alters the number and function of GABAergic interneurons in the murine orbitofrontal cortex.
Sign Up to like & getrecommendations! Published in 2020 at "Alcohol"
DOI: 10.1016/j.alcohol.2020.06.001
Abstract: Exposure to alcohol during development produces Fetal Alcohol Spectrum Disorders (FASD), characterized by a wide range of effects that include deficits in multiple cognitive domains. Early identification and treatment of individuals with FASD remains a… read more here.
Keywords: prenatal alcohol; function; exposure; moderate prenatal ... See more keywords
Adolescent alcohol exposure alters DNA and RNA modifications in peripheral blood by liquid chromatography-tandem mass spectrometry analysis
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.08.094
Abstract: ABSTRACT Alcohol consumption is a critical risk factor contributing to a verity of human diseases. The incidence of alcohol use disorder increases across adolescence in recent years. Accumulating line of evidence suggests that alcohol-induced changes… read more here.
Keywords: rna modifications; alcohol exposure; dna rna;
Prenatal alcohol exposure and facial morphology in a UK cohort.
Sign Up to like & getrecommendations! Published in 2019 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2018.11.031
Abstract: BACKGROUND High levels of prenatal alcohol exposure are known to cause an array of adverse outcomes including fetal alcohol syndrome (FAS); however, the effects of low to moderate exposure are less-well characterized. Previous findings suggest… read more here.
Keywords: prenatal alcohol; facial morphology; exposure; alcohol exposure ... See more keywords