Trends in Alcohol‐Induced Deaths in the United States by Sex, Age, and Ethnicity Suggest a Need for Targeted Health Interventions
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31562
Abstract: The study incorporated data from the entire US population for the period 2000 to 2016 by identifying the underlying cause of death that had been recorded on death certificates from the US National Center for… read more here.
Keywords: deaths united; death; trends alcohol; alcohol induced ... See more keywords
Vitamin D Deficiency Attenuates Acute Alcohol-Induced Hepatic Lipid Accumulation in Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Lipids"
DOI: 10.1002/lipd.12188
Abstract: Vitamin D deficiency has been frequently reported in chronic liver disease. However, its influence on hepatic lipid accumulation in alcoholic liver disease remains unclear. The present study investigated the effects of vitamin D deficiency on… read more here.
Keywords: hepatic lipid; lipid accumulation; alcohol induced; deficiency ... See more keywords
Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7383
Abstract: Costunolide (cos) derived from the roots of Dolomiaea souliei (Franch.), which belongs to the Dolomiaea genus in the family Compositae, exert the anti‐inebriation effect mainly by inhibiting the absorption of alcohol in the gastrointestinal tract.… read more here.
Keywords: liver injury; injury regulating; alcohol induced; induced liver ... See more keywords
Cellular and molecular mechanisms of alcohol-induced osteopenia
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DOI: 10.1007/s00018-017-2585-y
Abstract: Alcoholic beverages are widely consumed, resulting in a staggering economic cost in different social and cultural settings. Types of alcohol consumption vary from light occasional to heavy, binge drinking, and chronic alcohol abuse at all… read more here.
Keywords: induced osteopenia; cellular molecular; alcohol induced; bone ... See more keywords
Effects of sub-chronic amylin receptor activation on alcohol-induced locomotor stimulation and monoamine levels in mice
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05607-8
Abstract: Amylin receptors consist of the calcitonin receptor (CTR) and one of three receptor activity-modifying proteins (RAMPs). The identification of amylin receptors in areas processing reward, namely laterodorsal tegmental area (LDTg), ventral tegmental area (VTA), and… read more here.
Keywords: sub chronic; treatment; alcohol induced; receptor ... See more keywords
Extracellular Vesicles: Intercellular Mediators in Alcohol-Induced Pathologies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmune Pharmacology"
DOI: 10.1007/s11481-019-09848-z
Abstract: Though alcoholic liver injury plays the primary role in direct alcohol-related morbidity, alcohol consumption is also interlinked with many other diseases in extra-hepatic tissues/organs. The mechanism of alcoholic tissue injury is well documented, however the… read more here.
Keywords: extracellular vesicles; evs exosomes; hepatic tissues; extra hepatic ... See more keywords
Protective Effects of Donepezil Against Alcohol-Induced Toxicity in Cell Culture: Role of Caspase-3
Sign Up to like & getrecommendations! Published in 2018 at "Neurotoxicity Research"
DOI: 10.1007/s12640-018-9913-3
Abstract: Ethanol (EtOH) is one of the most frequently abused drugs with heavy health, economic, and societal burdens. Although moderate to low EtOH may have some neuroprotective effects, heavy EtOH consumption associated with high blood alcohol… read more here.
Keywords: caspase; etoh induced; toxicity; alcohol induced ... See more keywords
Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108677
Abstract: We investigate the effect of the alcohol-induced increase in the content of CYP2E1 in human liver microsomes (HLM) on the function of CYP3A4. Membrane incorporation of the purified CYP2E1 into HLM considerably increases the rate… read more here.
Keywords: induced increase; cyp2e1; hlm; alcohol induced ... See more keywords
PKA, PP1, and DC1 phosphorylation mediate alcohol-induced ciliary dysfunction in Chlamydomonas reinhardtii.
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DOI: 10.1016/j.alcohol.2018.05.001
Abstract: Excessive alcohol consumption impairs mucociliary clearance, in part, by compromising ciliary movement. Our previous study found alcohol reduces ciliary beat frequency in Chlamydomonas through a mechanism that involves the β and γ heavy chains of… read more here.
Keywords: alcohol induced; induced ciliary; alcohol; dc1 phosphorylation ... See more keywords
Purkinje cell-specific deletion of CREB worsens alcohol-induced cerebellar neuronal losses and motor deficits.
Sign Up to like & getrecommendations! Published in 2022 at "Alcohol"
DOI: 10.1016/j.alcohol.2022.02.005
Abstract: INTRODUCTION Exposure to alcohol during pregnancy can kill developing fetal neurons and lead to FASD in the offspring. However, not all fetuses are equally vulnerable to alcohol toxicity. These differences in vulnerability among individuals are… read more here.
Keywords: alcohol; cell; creb; purkinje cells ... See more keywords
Alcohol-Induced Amnesia and Personalized Drinking Feedback: Blackouts Predict Intervention Response.
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DOI: 10.1016/j.beth.2018.03.008
Abstract: Alcohol-induced amnesia ("blackout") is a reliable predictor of alcohol-related harm. Given its association with other negative consequences, experience of alcohol-induced amnesia may serve as a teachable moment, after which individuals are more likely to respond… read more here.
Keywords: intervention; feedback; alcohol induced; induced amnesia ... See more keywords