Free Cholesterol‐Induced Liver Injury in Non‐Alcoholic Fatty Liver Disease: Mechanisms and a Therapeutic Intervention Using Dihydrotanshinone I
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DOI: 10.1002/advs.202406191
Abstract: Build‐up of free cholesterol (FC) substantially contributes to the development and severity of non‐alcoholic fatty liver disease (NAFLD). Here, we investigate the specific mechanism by which FC induces liver injury in NAFLD and propose a… read more here.
Keywords: free cholesterol; non alcoholic; alcoholic fatty; liver disease ... See more keywords
Combined effects of vitamin D3 and dioxopiperidinamide derivative on lipid homeostasis, inflammatory pathways, and redox imbalance in non‐alcoholic fatty liver disease in vivo zebrafish model
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DOI: 10.1002/bab.2666
Abstract: Liver damage and metabolic dysfunctions, the defining features of non‐alcoholic fatty liver disease (NAFLD), are marked by inflammation, oxidative stress, and excessive hepatic fat accumulation. The current therapeutic approaches for NAFLD are limited, necessitating exploring… read more here.
Keywords: vit dopa; non alcoholic; alcoholic fatty; liver disease ... See more keywords
Non‐alcoholic fatty liver disease and heart failure with preserved ejection fraction: from pathophysiology to practical issues
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DOI: 10.1002/ehf2.13222
Abstract: The prevalence of non‐alcoholic fatty liver disease (NAFLD) in heart failure (HF) preserved left ventricular ejection fraction (HFpEF) patients could reach 50%. Therefore, NAFLD is considered an emerging risk factor. In 20% of NAFLD patients,… read more here.
Keywords: alcoholic fatty; fatty liver; heart failure; non alcoholic ... See more keywords
Dual roles of B lymphocytes in murine models of diet-induced non-alcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32428
Abstract: BACKGROUND & AIMS Growing evidence suggests an important role of B cells in the development of non-alcoholic fatty liver disease (NAFLD). However, a detailed functional analysis of B cell subsets in NAFLD pathogenesis is lacking.… read more here.
Keywords: igmi mice; liver disease; mice; alcoholic fatty ... See more keywords
Relationship between non-alcoholic fatty liver disease and coronary artery disease: A Mendelian randomization study.
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DOI: 10.1002/hep.32534
Abstract: BACKGROUND & AIMS There is an ongoing debate on whether non-alcoholic fatty liver disease (NAFLD) is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the… read more here.
Keywords: cad; fatty liver; disease; non alcoholic ... See more keywords
NRPT reduces markers of hepatic inflammation in non-alcoholic fatty liver disease: a double-blind, placebo-controlled clinical trial.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32778
Abstract: BACKGROUND & AIMS The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing globally on a path to becoming the most frequent cause of chronic liver disease. Novel strategies for the prevention and treatment of… read more here.
Keywords: decrease; alcoholic fatty; non alcoholic; placebo ... See more keywords
The association between non‐alcoholic fatty liver disease and serum ferritin levels in American adults
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24225
Abstract: Elevated serum ferritin levels (SFLs) was previously reported to be related with hepatic histologic severity and advanced liver fibrosis among non‐alcoholic fatty liver disease (NAFLD) patients. However, whether NAFLD influences SFLs remains uncertain and needs… read more here.
Keywords: alcoholic fatty; non alcoholic; fatty liver; ferritin levels ... See more keywords
Muscle strength, but not body mass index, is associated with mortality in patients with non‐alcoholic fatty liver disease
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DOI: 10.1002/jcsm.13001
Abstract: Whether adiposity and muscle function are associated with mortality risk in patients with non‐alcoholic fatty liver disease (NAFLD) remains unknown. We examine the independent and combined associations of body mass index (BMI) and muscle strength… read more here.
Keywords: alcoholic fatty; non alcoholic; muscle; patients non ... See more keywords
Different effects of low muscle mass on the risk of non‐alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13125
Abstract: Non‐alcoholic fatty liver disease (NAFLD) and sarcopenia share insulin resistance as a common pathophysiology and have overlapping clinical manifestation of metabolic derangement; hence, it is difficult to differentiate the independent effect of sarcopenia on the… read more here.
Keywords: alcoholic fatty; non alcoholic; fatty liver; muscle ... See more keywords
Physical frailty, genetic predisposition, and the risks of severe non‐alcoholic fatty liver disease and cirrhosis: a cohort study
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DOI: 10.1002/jcsm.13506
Abstract: Frailty, defined as a phenotype of decreased physiological reserves and diminished ability to respond to stressors, has been linked to the development of chronic diseases. Epidemiological evidence connecting frailty to non‐alcoholic fatty liver disease (NAFLD)… read more here.
Keywords: cirrhosis; non alcoholic; alcoholic fatty; frailty ... See more keywords
Body Composition and Progression of Biopsy‐Proven Non‐Alcoholic Fatty Liver Disease in Patients With Obesity
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DOI: 10.1002/jcsm.13605
Abstract: Obesity is a significant risk factor for the progression of non‐alcoholic fatty liver disease (NAFLD). However, a convenient and efficacious non‐invasive test for monitoring NAFLD progression in patients with obesity is currently lacking. This study… read more here.
Keywords: patients obesity; progression; non alcoholic; alcoholic fatty ... See more keywords