Alcoholic liver disease in relation to cancer incidence and mortality: Findings from a large, matched cohort study in South Korea
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5614
Abstract: To estimate the risk of cancer incidence and mortality among patients with alcoholic liver disease in South Korea. read more here.
Keywords: south korea; alcoholic liver; incidence mortality; liver disease ... See more keywords
Risk for alcoholic liver cirrhosis after an initial hospital contact with alcohol problems: A nationwide prospective cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28943
Abstract: Alcoholic liver cirrhosis is usually preceded by many years of heavy drinking, in which cessation in drinking could prevent the disease. Alcohol problems are not consistently managed in hospital patients. We followed all Danish patients… read more here.
Keywords: liver cirrhosis; risk; alcohol problems; alcoholic liver ... See more keywords
Gut‐Liver Axis Beyond the Microbiome: How the Fungal Mycobiome Contributes to Alcoholic Liver Disease
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DOI: 10.1002/hep.30055
Abstract: The importance of the “gut-liver axis” has been long established in alcoholic liver disease (ALD). The direct effects of alcohol, its metabolites, and reactive oxygen species produced during alcohol metabolism result in cellular stress in… read more here.
Keywords: gut; fungal mycobiome; alcoholic liver; disease ... See more keywords
Sea buckthorn (Hippophae rhamnoides L.) fermentation liquid protects against alcoholic liver disease linked to regulation of liver metabolome and the abundance of gut microbiota.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10915
Abstract: BACKGROUND Alcoholic liver disease (ALD) refers to liver damage caused by long-term heavy drinking, which causing oxidative stress and changes in gut microbiota. In this paper, we investigated the hepatoprotective effect of sea buckthorn fermentation… read more here.
Keywords: gut; alcoholic liver; sea buckthorn; gut microbiota ... See more keywords
Multi-omics integration reveals the hepatoprotective mechanisms of ursolic acid intake against chronic alcohol consumption
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nutrition"
DOI: 10.1007/s00394-021-02632-x
Abstract: Alcoholic liver disease (ALD) is a major health issue globally. In addition to pharmacotherapy, dietary support is also regarded as reliable strategy for ALD management. As a widely distributed natural constituent within edible plants, the… read more here.
Keywords: integration; alcoholic liver; ursolic acid; liver injury ... See more keywords
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09635-8
Abstract: Hepatocyte senescence is a key event participating in the progression of alcoholic liver disease. Autophagy is a critical biological process that controls cell fates by affecting cell behaviors like senescence. Pterostilbene is a natural compound… read more here.
Keywords: hepatocyte senescence; alcoholic liver; senescence; pterostilbene ... See more keywords
A Systems Biology Approach to Understanding Alcoholic Liver Disease Molecular Mechanism: The Development of Static and Dynamic Models
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-017-0336-8
Abstract: Alcoholic liver disease (ALD) is a complex disease characterized by damages to the liver and is the consequence of excessive alcohol consumption over years. Since this disease is associated with several pathway failures, pathway reconstruction… read more here.
Keywords: ald; network; alcoholic liver; disease ... See more keywords
Are Probiotics Effective in Targeting Alcoholic Liver Diseases?
Sign Up to like & getrecommendations! Published in 2018 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-018-9419-6
Abstract: Alcoholic liver disease (ALD) encompasses a broad spectrum of disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. Despite intensive research in the last two decades, there is currently no Food and Drug Administration-approved therapy for treating… read more here.
Keywords: alcoholic liver; probiotics effective; effective targeting; liver diseases ... See more keywords
Sulfated modification of the polysaccharides from Crassostrea gigas and their antioxidant and hepatoprotective activities through metabolomics analysis.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.02.053
Abstract: Sulfated polysaccharides from Crassostrea gigas (SCGP) were successfully prepared using chlorosulfonic acid-pyridine method. The structure of SCGP was determined by high performance liquid chromatography (HPLC), Fourier transform infrared spectrometry (FT-IR) and nuclear magnetic resonance (NMR).… read more here.
Keywords: alcoholic liver; analysis; crassostrea gigas; scgp ... See more keywords
In-depth investigation of the mechanisms of Echinacea purpurea polysaccharide mitigating alcoholic liver injury in mice via gut microbiota informatics and liver metabolomics.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.04.131
Abstract: Accumulating evidence suggests that the pathogenesis of alcoholic liver disease (ALD) is strongly correlated with abnormalities of the gut-liver axis. Echinacea purpurea polysaccharide (EPP) is a homogeneous polysaccharide, which has been shown to mitigate ALD.… read more here.
Keywords: alcoholic liver; microbiota; purpurea polysaccharide; echinacea purpurea ... See more keywords
Wogonin attenuates inflammation by activating PPAR‐&ggr; in alcoholic liver disease
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.06.013
Abstract: Abstract Alcoholic liver disease (ALD) is one of the predominant causes of liver‐related morbidity and mortality worldwide. However, effective therapy for ALD is still lacking. Wogonin, a major flavonoid compound, is found in Scutellaria baicalensis… read more here.
Keywords: ppar; wogonin; alcoholic liver; ppar ggr ... See more keywords