Zn(II)-catalysed enantioselective addition of alcohols and tert-butyl hydroperoxide to isatin-derived N-Boc ketimines.
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DOI: 10.1039/d3cc01527k
Abstract: Using binaphthyl-proline-based chiral ligands, Zn(II)-catalysed addition of alcohols and tert-butyl hydroperoxide to isatin-derived N-Boc ketimines provided the isatin-derived C3 N,O-aminals in up to 99% yield and up to 99% ee. The reactions could be carried… read more here.
Keywords: butyl hydroperoxide; isatin; alcohols tert; addition alcohols ... See more keywords