Phosphoric Acid Catalyzed Aldehyde Addition to in Situ Generated o-Quinone Methides: An Enantio- and Diastereoselective Entry toward cis-3,4-Diaryl Dihydrocoumarins.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b01865
Abstract: A highly stereoselective, phosphoric acid catalyzed synthesis of cis-3,4-diarylchromanols through reaction of o-hydroxybenzhydryl alcohols and aryl acetaldehydes is reported. The products can be further manipulated to 3,4-dihydrocoumarins, 4 H-chromenes, and chromanes with good overall yields… read more here.
Keywords: cis; quinone methides; aldehyde addition; phosphoric acid ... See more keywords
Adaptable to Mechanically Stable Hydrogels Based on the Dynamic Covalent Cross-Linking of Thiol-Aldehyde Addition
Sign Up to like & getrecommendations! Published in 2019 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.9b00020
Abstract: We exploit the thiol-aldehyde addition (TAA) reaction to build a dynamic covalent cross-linking (DCC) hydrogel in the physiological-pH environment. Due to the rapid and reversible TAA reaction, the resulting hydrogels are readily adapted for convenient… read more here.
Keywords: cross linking; thiol aldehyde; dynamic covalent; aldehyde addition ... See more keywords