A 3D-QSAR assisted activity prediction strategy for expanding substrate spectra of an aldehyde ketone reductase
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2018.06.013
Abstract: Abstract Aldo-keto reductases (AKRs) are widely used for reducing prochiral aldehyde or ketone compounds into corresponding chiral alcohols. In our previous work, an aldo-keto reductase named YtbE was isolated and identified from Bacillus sp. ECU0013,… read more here.
Keywords: qsar assisted; activity; substrate; aldehyde ketone ... See more keywords
Aldehyde/ketone-catalyzed highly selective synthesis of 9-monoalkylated fluorenes by dehydrative C-alkylation with primary and secondary alcohols
Sign Up to like & getrecommendations! Published in 2017 at "Green Chemistry"
DOI: 10.1039/c6gc02518h
Abstract: By using aldehydes or ketones as the catalyst and screening CsOH out as the more effective base than KOH in many instances, an efficient 9-C-alkylation of fluorenes with alcohols was achieved to provide a green… read more here.
Keywords: monoalkylated fluorenes; aldehyde ketone; primary secondary; secondary alcohols ... See more keywords