Major aldehyde dehydrogenase AldFGH of Gluconacetobacter diazotrophicus is independent of pyrroloquinoline quinone but dependent on molybdopterin for acetic acid fermentation.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11144-x
Abstract: Acetic acid fermentation involves the oxidation of ethanol to acetic acid via acetaldehyde as the intermediate and is catalyzed by the membrane-bound alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) of acetic acid bacteria. Although ADH… read more here.
Keywords: acid fermentation; aldh activity; acetic acid; activity ... See more keywords
Abstract 3685: The BET inhibitor INCB057643 suppresses ALDH activity by targeting the ALDH1A1 super-enhancer in high-grade serous ovarian cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3685
Abstract: The emergence of tumor cells with certain stem-like characteristics such as high aldehyde dehydrogenase (ALDH) activity due to ALDH1A1 expression contributes to chemotherapy resistance and tumor relapse. However, clinically applicable inhibitors of ALDH activity have… read more here.
Keywords: bet; ovarian cancer; cancer; aldh activity ... See more keywords
Linking ALDH1 and retinoic acid signaling
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DOI: 10.18632/oncotarget.26661
Abstract: All-trans retinoic acid (ATRA) is an effective therapy to treat acute promyelocytic leukemia. Its role in colorectal cancer is less well understood, in part, since it has not been fully established which cell types express… read more here.
Keywords: aldh activity; stem cells; activity; retinoic acid ... See more keywords