Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology and Toxicology"
DOI: 10.1007/s10565-018-9444-y
Abstract: Aldehyde dehydrogenases (ALDHs) defend intracellular homeostasis by catalyzing the conversion of toxic aldehydes into non-toxic carboxylic acids, which is of particular importance to the self-renewal of stem cells and cancer stem cells. The widely used… read more here.
Keywords: aldh isoforms; cancer type; aldefluor assay; expression ... See more keywords
Profiling of Aldehyde Dehydrogenase Isoforms in In Vitro Formed Tumorspheres
Sign Up to like & getrecommendations! Published in 2021 at "AntiCancer Research"
DOI: 10.21873/anticanres.15361
Abstract: Background/Aim: Aldehyde dehydrogenases (ALDHs) are considered as markers for normal and cancer stem cells (CSC) and are involved in cell metabolism, proliferation, differentiation, stemness, and retinoic acid (RA) biosynthesis. The aim of the present study… read more here.
Keywords: aldh isoforms; profiling aldehyde; vitro formed; isoforms vitro ... See more keywords