Inhalation exposure to low levels of ethyl tertiary butyl ether: Its genetic effects were significantly modified by ALDH2 activity
Sign Up to like & getrecommendations! Published in 2019 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22256
Abstract: Previous experiments showed that high concentrations of ethyl tertiary butyl ether (ETBE) exposure (500–5,000 ppm) significantly resulted in DNA damages in aldehyde dehydrogenase 2 (Aldh2) knockout (KO) mice. This study was aimed to verify the… read more here.
Keywords: aldh2 activity; genetic effects; tertiary butyl; butyl ether ... See more keywords
Detecting ALDH2 activity in live cells via conditional metabolic labeling
Sign Up to like & getrecommendations! Published in 2025 at "Chemical Science"
DOI: 10.1039/d5sc04198h
Abstract: Detecting enzyme activity that catalyzes subtle functional group transformations in live cells remains a major challenge. We introduce a conditional metabolic labeling strategy for enzymatic activity detection (cMLEAD), which harnesses cellular metabolic pathways to deliver… read more here.
Keywords: conditional metabolic; metabolic labeling; live cells; aldh2 activity ... See more keywords